Evidence map›Paper›PMID 30797507›Full record

ReviewCurrent topics in developmental biology2019

Chasing Mavericks: The quest for defining developmental waves of hematopoiesis.

Taylor Cool, E Camilla Forsberg

Abstract readReview
In one paragraph

Review in Current topics in developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Immune Factors, Immune Cells and Inflammatory Diseases.International journal of molecular sciences · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Taylor CoolInstitute for the Biology of Stem Cells, Program in Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
E Camilla ForsbergInstitute for the Biology of Stem Cells, Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA, United States. Electronic address: cforsber@ucsc.edu.

Funding

Role and Regulation of a Novel, Developmentally Restricted Hematopoietic Stem CellR01DK100917 · NIDDK · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI FORSBERG, CAMILLA · 2013 to 2024
$3.9M
Regulation of Chromatin Structure Dynamics in Hematopoietic and Leukemic Stem CelR01HL115158 · NHLBI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI FORSBERG, CAMILLA · 2013 to 2017
$2.1M
NHLBI NIH HHS R01 HL115158NIDDK NIH HHS R01 DK100917
6 · The paper itself

Abstract

Hematopoiesis is the process by which mature blood and immune cells are produced from hematopoietic stem and progenitor cells (HSCs and HSPCs). The last several decades of research have shed light on the origin of HSCs, as well as the heterogeneous pools of fetal progenitors that contribute to lifelong hematopoiesis. The overarching concept that hematopoiesis occurs in dynamic, overlapping waves throughout development, with each wave contributing to both continuous and developmentally limited cell types, has been solidified over the years. However, recent advances in our ability to track the production of hematopoietic cells in vivo have challenged several long-held dogmas on the origin and persistence of distinct hematopoietic cell types. In this review, we highlight emerging concepts in hematopoietic development and identify unanswered questions.

Indexed as

AnimalsCell DifferentiationCell LineageEmbryo, MammalianEmbryonic Stem CellsFetal Stem CellsHematopoiesisHematopoietic Stem CellsHumansAdaptive immune cellsBlood and immune cellsBlood developmentDevelopmentDifferentiationHematopoiesisHematopoietic progenitor cellsHematopoietic stem cellsImmune developmentInnate immune cellsSelf-renewalSpecificationTissue-resident cells

Identifiers

PMID30797507
PMCPMC9107351

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.