Evidence map›Paper›PMID 30796711›Full record

ArticlePlant molecular biology2019

Increased fes1a thermotolerance is induced by BAG6 knockout.

Can Fu, Yanfei Hou, Jingjing Ge, Limin Zhang, Xiaxia Liu, Panfei Huo, Jian Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Plant molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Identification and evaluation ofFrontiers in genetics · 2024
    Article
  5. Article
  6. Review
  7. Distribution, expression of hexaploid wheatFrontiers in plant science · 2022
    Article
  8. Article
  9. Article
  10. TheInternational journal of molecular sciences · 2021
    Article
  11. Heat-Induced Oxidation of the Nuclei and Cytosol.Frontiers in plant science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Can FuCollege of Life Science, Shandong Normal University, Jinan, 250014, Shandong, China.
Yanfei HouCollege of Life Science, Shandong Normal University, Jinan, 250014, Shandong, China.
Jingjing GeCollege of Life Science, Shandong Normal University, Jinan, 250014, Shandong, China.
Limin ZhangCollege of Life Science, Shandong Normal University, Jinan, 250014, Shandong, China.
Xiaxia LiuCollege of Life Science, Shandong Normal University, Jinan, 250014, Shandong, China.
Panfei HuoCollege of Life Science, Shandong Normal University, Jinan, 250014, Shandong, China.
Jian LiuCollege of Life Science, Shandong Normal University, Jinan, 250014, Shandong, China. ljlsd2002@aliyun.com.
Shandong Normal University · CNGuilin Medical University · CN

Funding

National Natural Science Foundation of China 31270298Research Fundamental Capacity Improvement Project for Middle Age and Youth Teachers of Guangxi Universities (CN) 2019KY0517
6 · The paper itself

Abstract

key message(1) The fes1a bag6 double mutant shows an increased short term thermotolerance compared to fes1a. BAG6 is a suppressor of Fes1A; (2) IQ motif is essential to effective performance of BAG6. (3) Calmodulin was involved in signal transduction. (4) BAG6 is localized in the nucleus. HSP70s play an important role in the heat-induced stress tolerance of plants. However, effective HSP70 function requires the assistance of many co-chaperones. BAG6 and Fes1A are HSP70-binding proteins that are critical for Arabidopsis thaliana thermotolerance. Despite this importance, little is known about how these co-chaperones interact. In this study, we assessed the thermotolerance of a fes1a bag6 double mutant. We found that the fes1a bag6 double mutant shows an increased short-term thermotolerance compared to fes1a. However, calmodulin inhibitors diminished this enhanced thermotolerance in the fes1a bag6 double mutant. In addition, we found the IQ motif to be essential for effective BAG6 performance. Since BAG6 is localized in the nucleus, the signal transduction is likely to involve nuclear calcium signaling.

Indexed as

Gene Knockout TechniquesThermotoleranceArabidopsisArabidopsis ProteinsCalmodulinCarrier ProteinsCell NucleusGene Expression Regulation, PlantHeat-Shock ProteinsHot TemperatureHSP70 Heat-Shock ProteinsMolecular ChaperonesMutationNuclear ProteinsProtein BindingArabidopsis ProteinsBAG6 protein, ArabidopsisCalmodulinCarrier ProteinsFES1 protein, ArabidopsisHeat-Shock ProteinsHSP70 Heat-Shock ProteinsMolecular ChaperonesNuclear ProteinsBAG6CalmodulinIQ motifSuppressor

Identifiers

PMID30796711
OpenAlexW2915173628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.