Evidence map›Paper›PMID 30796519›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019

Caregivers' burden and fatigue during and after patients' treatment with concomitant chemoradiotherapy for locally advanced head and neck cancer: a prospective, observational pilot study.

Simone M C H Langenberg, Carla M L van Herpen, Claudia C M van Opstal, Anke N M Wymenga, Winette T A van der Graaf, Judith B Prins

Abstract readObservational Study
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Caregiver burden, anxiety, and quality-of-life among informal caregivers of patient with head and neck cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Self-perception of fatigue in individuals diagnosed with head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. "It's part of our life now": a qualitative exploration of the social eating experiences of family members of patients living with head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  10. "My life's not my own": A qualitative study into the expectations of head and neck cancer carers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  11. Self-care, resilience, and caregiver burden in relatives of patients with advanced cancer: results from the eQuiPe study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Observational
  12. Article
  13. Informal caregiver well-being during and after patients' treatment with adjuvant chemotherapy for colon cancer: a prospective, exploratory study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  14. Providing care to a family member affected by head and neck cancer: a phenomenological study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simone M C H LangenbergDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-8085-0392
Carla M L van HerpenDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
Claudia C M van OpstalDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
Anke N M WymengaDepartment of Medical Oncology, Medisch Spectrum Twente, Enschede, The Netherlands.
Winette T A van der GraafDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
Judith B PrinsDepartment of Medical Psychology, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen (840), The Netherlands. judith.prins@radboudumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeKnowledge of caregivers' burden and fatigue before and after patients' treatment for locally advanced head and neck cancer is scarce. Therefore, we aimed to explore caregivers' fatigue and burden in relation to patients' fatigue, distress, and quality of life.

methodsFor caregivers, burden and fatigue were assessed. For patients, fatigue severity, distress, and health-related quality of life (HRQoL) were assessed. Measurements were conducted prior to treatment, 1 week, and 3 months after chemoradiotherapy.

resultsCaregivers' burden and fatigue followed patients' high peak in distress, fatigue, and diminished HRQoL as a consequence of treatment. Caregivers' baseline fatigue was a predictor for fatigue after chemoradiotherapy. Female spouses with higher baseline levels of fatigue and burden and caring for patients with lower levels of HRQoL seem risk factors for burden after chemoradiotherapy.

conclusionsAttention should be paid to caregivers' burden and fatigue before starting patients' intense treatment with chemoradiotherapy, as both burden and fatigue before starting treatment may contribute to burden and fatigue after chemoradiotherapy.

Indexed as

ChemoradiotherapyAdaptation, PsychologicalAdultCaregiversFatigueFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPilot ProjectsProspective StudiesQuality of LifeSpousesSurveys and QuestionnairesBurdenCaregiverChemoradiotherapyFatigueLAHNC

Identifiers

PMID30796519
PMCPMC6803613

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.