Evidence map›Paper›PMID 30796491›Full record

ArticlePsychopharmacology2019

The role of E-liquid vegetable glycerin and exhaled aerosol on cue reactivity to tank-based electronic nicotine delivery systems (ENDS).

Ashley Vena, Meghan Howe, Dingcai Cao, Andrea King

Abstract read
In one paragraph

Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  2. Cue Reactivity Effects of Heated Tobacco Product Use in Current, Former, and Never Smokers in the United States.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  3. Cue Reactivity to Electronic Cigarettes: A Systematic Review.Substance abuse : research and treatment · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashley VenaDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, 5841 S. Maryland Avenue (MC-3077), Chicago, IL, 60637, USA.
Meghan HoweDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, 5841 S. Maryland Avenue (MC-3077), Chicago, IL, 60637, USA.
Dingcai CaoDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Andrea KingDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, 5841 S. Maryland Avenue (MC-3077), Chicago, IL, 60637, USA. aking@yoda.bsd.uchicago.edu.ORCID http://orcid.org/0000-0001-5943-7109

Funding

Integrative Training in the Neurobiology of Addictive BehaviorsT32DA043469 · NIDA · UNIVERSITY OF CHICAGO · PI Donald Hedeker, Xiaoxi Zhuang · 2017 to 2026
$3.8M
E-cigarette use as a smoking cueR01DA044210 · NIDA · UNIVERSITY OF CHICAGO · PI KING, ANDREA C · 2018 to 2021
$2.1M
Women's Response to E-Cigarette Cues R56DA044210 · NIDA · UNIVERSITY OF CHICAGO · PI KING, ANDREA C · 2017 to 2017
$300k
National Institute on Drug Abuse R56-DA044210National Institute on Drug Abuse T32-DA043469NIDA NIH HHS R01 DA044210NIDA NIH HHS R56 DA044210NIDA NIH HHS T32 DA043469University of Chicago, Department of Psychiatry and Behavioral Neuroscience Research Faculty Fund
6 · The paper itself

Abstract

rationaleElectronic nicotine delivery systems (ENDS or e-cigarettes) share salient features of combustible smoking, such as inhalation and exhalation behaviors, and evidence indicates that first- and second-generation ENDS generalize as smoking cues. The present study examined whether newer, tank-based third-generation ENDS ("mods") also evoke smoking urges, and whether enhancing the visibility of exhaled aerosol clouds-by increasing the e-liquid vegetable glycerin (VG) content-strengthens the cue salience of ENDS.

objectivesThe objective was to assess the role of exhaled aerosol clouds on ENDS cue potency using a standardized laboratory paradigm designed to mimic real-world exposures.

methodsUsing a mixed design, young adult smokers (n = 50; mean age 26.5 years; ≥ 5 cigarettes/day) observed a study confederate drinking bottled water (control cue) and vaping an ENDS mod containing e-liquid with either high (73%) or low (0%) VG. Participants completed the Brief Questionnaire on Smoking Urges (BQSU) and visual analog scales (VAS) assessing cigarette and e-cigarette desire pre- and post-cue exposure.

resultsIncreasing the e-liquid content of VG enhanced the size and visibility of the exhaled aerosol clouds and evoked a greater increase in smoking desire and a more sustained increase in e-cigarette desire relative to the low VG cue. Both cues elicited increases in smoking urges. These results remained after controlling for sex, prior ENDS experience, recent smoking behavior, and menthol preference.

conclusionsObservation of tank-based ENDS use generalizes as a smoking cue and its cue salience is strengthened by increasing the e-liquid content of VG to enhance the visibility of the exhaled aerosol cloud.

Indexed as

CuesVegetablesAdultAerosolsCravingElectronic Nicotine Delivery SystemsExhalationFemaleGlycerolHumansMaleSmokersSurveys and QuestionnairesVapingYoung AdultAerosolsGlycerolCuesElectronic cigarettesElectronic nicotine delivery systemsModsUrgeVapingVegetable glycerin

Identifiers

PMID30796491
PMCPMC6626688

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.