ArticleScientific reports2019
Choosing a laser for laser speckle contrast imaging.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Advanced optical phantom mimicking microvascular and directed blood flow in mouse brain.Biomedical engineering letters · 2026Article
- Cardiac pulse transfer along the cerebral microvascular network captured by laser speckle contrast imaging.Biomedical optics express · 2026Article
- Lightweight denoising speckle contrast image GAN for real-time denoising of laser speckle imaging of blood flow.Biomedical optics express · 2025Article
- Machine Learning-Based Approach towards Identification of Pharmaceutical Suspensions Exploiting Speckle Pattern Images.Sensors (Basel, Switzerland) · 2024Article
- Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow.Nature communications · 2024Article
- Article
- Comprehensive workflow and its validation for simulating diffuse speckle statistics for optical blood flow measurements.Biomedical optics express · 2024Article
- Dynamic light scattering and laser speckle contrast imaging of the brain: theory of the spatial and temporal statistics of speckle pattern evolution.Biomedical optics express · 2024Article
- Choosing a polarisation configuration for dynamic light scattering and laser speckle contrast imaging.Biomedical optics express · 2024Article
- Optimizing the precision of laser speckle contrast imaging.Scientific reports · 2023Article
- Design and validation of a convolutional neural network for fast, model-free blood flow imaging with multiple exposure speckle imaging.Biomedical optics express · 2023Article
- Quasi-analytic solution for real-time multi-exposure speckle imaging of tissue perfusion.Biomedical optics express · 2023Article
- Neurovascular Uncoupling Is Linked to Microcirculatory Dysfunction in Regions Outside the Ischemic Core Following Ischemic Stroke.Journal of the American Heart Association · 2023Article
- A quasi-analytic solution for real-time multi-exposure speckle imaging of tissue perfusion.bioRxiv : the preprint server for biology · 2023Article
- Lossless temporal contrast analysis of laser speckle images from periodic signals.Biomedical optics express · 2023Article
- All fiber-based illumination system for multi-exposure speckle imaging.Biomedical optics express · 2023Article
- Model of dynamic speckle evolution for evaluating laser speckle contrast measurements of tissue dynamics.Biomedical optics express · 2022Article
- Laser speckle simulation tool based on stochastic differential equations for bio imaging applications.Biomedical optics express · 2022Article
- Demystifying speckle field interference microscopy.Scientific reports · 2022Article
- Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity.Biomedical optics express · 2022Article
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4 authors.
Funding
Abstract
The use of laser speckle contrast imaging (LSCI) has expanded rapidly for characterizing the motion of scattering particles. Speckle contrast is related to the dynamics of the scattering particles via a temporal autocorrelation function, but the quality of various elements of the imaging system can adversely affect the quality of the signal recorded by LSCI. While it is known that the laser coherence affects the speckle contrast, it is generally neglected in in vivo LSCI studies and was not thoroughly addressed in a practical matter. In this work, we address the question of how the spectral width of the light source affects the speckle contrast both experimentally and through numerical simulations. We show that commonly used semiconductor laser diodes have a larger than desired spectral width that results in a significantly reduced speckle contrast compared with ideal narrow band lasers. This results in a reduced signal-to-noise ratio for estimating changes in the motion of scattering particles. We suggest using a volume holographic grating stabilized laser diode or other diodes that have a spectrum of emitted light narrower than ≈1 nm to improve the speckle contrast.
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