Evidence map›Paper›PMID 30796229›Full record

ArticleScientific reports2019

Photoacoustic transfection of DNA encoding GFP.

Alexandre D Silva, Carlos Serpa, Luis G Arnaut

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexandre D SilvaCQC, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal.
Carlos SerpaCQC, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal. serpasoa@ci.uc.pt.ORCID 0000-0001-7004-0110
Luis G ArnautCQC, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal. lgarnaut@ci.uc.pt.ORCID 0000-0002-3223-4819
University of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoacoustic transfection consists in the use of photoacoustic waves, generated in the thermoelastic expansion of a confined material absorbing a short pulse of a laser, to produce temporary mechanical deformations of the cell membrane and facilitate the delivery of plasmid DNA into cells. We show that high stress gradients, produced when picosecond laser pulses with a fluence of 100 mJ/cm

Indexed as

AnimalsCell MembraneChlorocebus aethiopsCOS CellsGreen Fluorescent ProteinsHumansPhotoacoustic TechniquesPlasmidsTransfectionGreen Fluorescent Proteins

Identifiers

PMID30796229
PMCPMC6384874
OpenAlexW2915755709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.