ArticleBMJ case reports2019
Neurosyphilis presenting as cranial nerve palsy, an entity which is easy to miss.
Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Neurosyphilis Presenting with Isolated Abducens Nerve Palsy.Internal medicine (Tokyo, Japan) · 2025Article
- Serial Changes in Magnetic Resonance Imaging During the Acute Phase of Neurosyphilis With Trigeminal Nerve Palsy.Cureus · 2025Article
- Acute Febrile Illness Accompanied by 7th and 12th Cranial Nerve Palsy Due to Lyme Disease Following Travel to Rural Ecuador: A Case Report and Mini-Review.Tropical medicine and infectious disease · 2025Article
- Review
- [Radiological clinical profile of multiple cranial neuropathy and recurrence risk factors].Revista medica del Instituto Mexicano del Seguro Social · 2024Observational
- Article
- MRI of neurosyphilis with mesiotemporal lobe lesions of "knife-cut sign" on MRI: A case report and literature review.Heliyon · 2023Article
- Facial nerve palsy: An early sign of COVID-19.Germs · 2023Article
- Neurosyphilis in disguise.Neuroradiology · 2022Review
- Syphilitic meningitis presenting with multiple cranial neuropathies.BMJ case reports · 2021Article
- Neurosyphilis in AIDS patient presenting as isolated cranial nerve 6 palsy.Clinical case reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurosyphilis is a rare disease that until the 2000s was almost eradicated due to population awareness of HIV and efficient treatment. Since then, the prevalence of the entity is rising due to risk-associated behaviour such as unprotected intercourse. Neurosyphilis is still a difficult entity to diagnose especially when combined with acute HIV infection which can influence the usual clinical course of disease. In rare occasions, both acute HIV and early syphilis infection can present as mono or multiple cranial nerve palsies. This case demonstrates a rare manifestation of misdiagnosed early syphilis infection combined with acute HIV infection in a 34-year-old man with prior history of unprotected sex with men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.