Evidence map›Paper›PMID 30796052›Full record

ArticleCancer research2019

Shandy Shahabi, Vishaly Kumaran, Jonathan Castillo, Zhengmin Cong, Gopika Nandagopal, Daniel J Mullen, Alexander Alvarado, Michele Ramos Correa, Autumn Saizan, Riya Goel and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 88 citations in OpenAlex.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Shandy Shahabi *Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Vishaly Kumaran *Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Jonathan CastilloDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Zhengmin CongDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Gopika NandagopalDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Daniel J MullenDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Alexander AlvaradoDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Michele Ramos CorreaNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Autumn SaizanNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Riya GoelNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Amrita BhatNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Sean K LynchDepartment of Product Engineering, Division of Manufacturing Operations, MAXIM Integrated Products, Sunnyvale, California.
Beiyun ZhouNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Zea BorokDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Crystal N MarconettDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California. Crystal.Marconett@med.usc.edu.
University of Southern California · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
Beyond the Barrier: Alveolar Epithelial Cell Biology in Health and DiseaseR35HL135747 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BOROK, ZEA · 2017 to 2023
$6.8M
Role of Chaperone GRP78 and Mitochondrial Dysfunction in ER Stress-Mediated Pulmonary FibrosisR01HL114959 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ANN, DAVID K., ZHOU, BEIYUN · 2013 to 2025
$4.2M
NCI NIH HHS P30 CA014089NHLBI NIH HHS R01 HL114959NHLBI NIH HHS R35 HL135747
6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer-related death in the United States. Long noncoding RNAs (lncRNA) are a class of regulatory molecules whose role in lung carcinogenesis is poorly understood. In this study, we profiled lncRNA expression in lung adenocarcinoma (LUAD) cell lines, compared their expression with that of purified alveolar epithelial type II cells (the purported cell of origin for LUAD), cross-referenced these with lncRNAs altered in the primary human tumors, and interrogated for lncRNAs whose expression correlated with patient survival. We identified

Indexed as

Cell ProliferationDNA DamageGenes, Tumor SuppressorHumansLung NeoplasmsRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID30796052
PMCPMC6571057
OpenAlexW2917151544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.