Evidence map›Paper›PMID 30796038›Full record

ArticleGenome research2019

TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells.

Kasper D Rasmussen, Ivan Berest, Sandra Keβler, Koutarou Nishimura, Lucía Simón-Carrasco, George S Vassiliou, Marianne T Pedersen, Jesper Christensen, Judith B Zaugg, Kristian Helin

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 93 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Kasper D Rasmussen *Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Ivan Berest *European Molecular Biology Institute, Structural and Computational Unit, 69115 Heidelberg, Germany.
Sandra KeβlerBiotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Koutarou NishimuraBiotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Lucía Simón-CarrascoBiotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
George S VassiliouWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB2 0XY, United Kingdom.ORCID 0000-0003-4337-8022
Marianne T PedersenBiotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Jesper ChristensenBiotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Judith B ZauggEuropean Molecular Biology Institute, Structural and Computational Unit, 69115 Heidelberg, Germany.ORCID 0000-0001-8324-4040
Kristian HelinBiotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-1975-6097
University of Copenhagen · DKEuropean Molecular Biology Laboratory · DECambridge University Hospitals NHS Foundation Trust · GB

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Cancer Research UK 23015Medical Research Council MC_PC_12009NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The epigenetic regulator

Indexed as

Enhancer Elements, GeneticAnimalsBasic Helix-Loop-Helix ProteinsCell LineCells, CulturedChromatinDioxygenasesDNA-Binding ProteinsEpigenesis, GeneticGene Expression Regulation, NeoplasticHematopoietic Stem CellsLeukemia, Myeloid, AcuteMiceProtein BindingProto-Oncogene ProteinsBasic Helix-Loop-Helix ProteinsChromatinDioxygenasesDNA-Binding ProteinsProto-Oncogene ProteinsTet2 protein, mouse

Identifiers

PMID30796038
PMCPMC6442383
OpenAlexW2952280017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.