Evidence map›Paper›PMID 30795607›Full record

ArticleCancers2019

The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.

Paul Hofman, Nicholas Ayache, Pascal Barbry, Michel Barlaud, Audrey Bel, Philippe Blancou, Frédéric Checler, Sylvie Chevillard, Gael Cristofari, Mathilde Demory and 17 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 7 institutions in 1 country.

Paul HofmanLaboratory of Clinical and Experimental Pathology/Biobank 0033-00025, CHU Nice, FHU OncoAge, Université Côte d'Azur, 06001 Nice, France. hofman.p@chu-nice.fr.
Nicholas AyacheEpione Team, Inria, FHU OncoAge, Université Côte d'Azur, 06902 Sophia Antipolis, France. Nicholas.ayache@inria.fr.
Pascal BarbryCNRS UMR7275, Institut de Pharmacologie Cellulaire et Moléculaire, FHU OncoAge, Université Côte d'Azur, 06560 Valbonne, France. pascal.barbry@unice.fr.
Michel Barlaudi3S Sophia Antipolis, FHU OncoAge, Université Côte d'Azur, 06560 Sophia Antipolis, France. michel.barlaud@unice.fr.
Audrey BelCentre d'Innovation et d'Usages en Santé (CIUS), FHU OncoAge, Université Côte d'Azur, 06000 Nice, France. audrey.bel@ciusante.org.
Philippe BlancouCNRS UMR7275, Institut de Pharmacologie Cellulaire et Moléculaire, FHU OncoAge, Université Côte d'Azur, 06560 Valbonne, France. philippe.blancou@unice.fr.
Frédéric CheclerCNRS UMR7275, Institut de Pharmacologie Cellulaire et Moléculaire, FHU OncoAge, Université Côte d'Azur, 06560 Valbonne, France. frederic.checler@unice.fr.
Sylvie ChevillardLaboratoire de Cancérologie Expérimentale, Institut François Jacob, CEA Direction de la Recherche Fondamentale, FHU OncoAge, Université Côte d'Azur, 92265 Fontenay-aux-Roses, France. sylvie.chevillard@cea.fr.
Gael CristofariInserm U1081, CNRS UMR7284, Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), FHU OncoAge, Université Côte d'Azur, 06107 Nice, France. gael.cristofari@unice.fr.
Mathilde DemoryVille de Nice, Mairie de Nice, FHU OncoAge, Université Côte d'Azur, 06364 Nice, France. mathilde.demory@ville-nice.fr.
Vincent EsnaultNephrology Department, CHU Nice, FHU OncoAge, Université Côte d'Azur, 06001 Nice, France. esnault.v@chu-nice.fr.
Claire FalandryGeriatric Unit, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, FHU OncoAge, Université Claude Bernard Lyon 1, 69310 Pierre-Benite, France. Claire.falandry@chu-lyon.fr.
Eric GilsonInserm U1081, CNRS UMR7284, Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), FHU OncoAge, Université Côte d'Azur, 06107 Nice, France. eric.gilson@unice.fr.
Olivier GuérinGeriatric Coordination Unit for Geriatric Oncology (UCOG) PACA Est, CHU Nice, FHU OncoAge, Université Côte d'Azur, 06000 Nice, France. guerin.o@chu-nice.fr.
Nicolas GlaichenhausCNRS UMR7275, Institut de Pharmacologie Cellulaire et Moléculaire, FHU OncoAge, Université Côte d'Azur, 06560 Valbonne, France. nicolas.glaichenhaus@unice.fr.
Joel GuigayOncology Department, Centre Antoine Lacassagne, FHU OncoAge, Université Côté d'Azur, 06189 Nice, France. joel.guigay@nice.unicancer.fr.
Marius IliéLaboratory of Clinical and Experimental Pathology/Biobank 0033-00025, CHU Nice, FHU OncoAge, Université Côte d'Azur, 06001 Nice, France. Ilie.m@chu-nice.fr.ORCID 0000-0002-2014-1236
Bernard MariCNRS UMR7275, Institut de Pharmacologie Cellulaire et Moléculaire, FHU OncoAge, Université Côte d'Azur, 06560 Valbonne, France. bernard.mari@unice.fr.ORCID 0000-0002-0422-9182
Charles-Hugo MarquetteDepartment of Pulmonary Medicine and Oncology, CHU Nice, FHU OncoAge, Université Côte d'Azur, 06000 Nice, France. marquette.c@chu-nice.fr.ORCID 0000-0002-0846-9941
Véronique Paquis-FlucklingerInserm U1081, CNRS UMR7284, Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), FHU OncoAge, Université Côte d'Azur, 06107 Nice, France. veronique.paquis@unice.fr.
Frédéric PrateGeriatric Coordination Unit for Geriatric Oncology (UCOG) PACA Est, CHU Nice, FHU OncoAge, Université Côte d'Azur, 06000 Nice, France. prate.f@chu-nice.fr.
Pierre SaintignyDépartement de Médecine, INSERM 1052, CNRS 5286, Centre de recherche en cancérologie de Lyon, Centre Léon Bérard, FHU OncoAge, Université Claude Bernard Lyon 1, 69008 Lyon, France. pierre.saintigny@lyon.unicancer.fr.
Barbara Seitz-PolskyCNRS UMR7275, Institut de Pharmacologie Cellulaire et Moléculaire, FHU OncoAge, Université Côte d'Azur, 06560 Valbonne, France. Seitz-polski.b@chu-nice.fr.
Taycir SkhiriCentre d'Innovation et d'Usages en Santé (CIUS), FHU OncoAge, Université Côte d'Azur, 06000 Nice, France. Skhiri.t@chu-nice.fr.
Ellen Van Obberghen-SchillingCNRS, Inserm, iBV, Centre Antoine Lacassagne, FHU OncoAge, Université Côte d'Azur, 06108 Nice, France. ellen.van-obberghen@unice.fr.ORCID 0000-0003-2961-0059
Emmanuel Van ObberghenCNRS, LP2M, FHU OncoAge, Université Côte d'Azur, 06107 Nice, France. emmanuel.Van-obberghen@unice.fr.
Laurent Yvan-CharvetInserm U1065, Centre Méditerranéen de Médecine Moléculaire (C3M), FHU OncoAge, Université Côte d'Azur, 06200 Nice, France. laurent.yvan-charvet@unice.fr.
Centre National de la Recherche Scientifique · FRUniversité Côte d'Azur · FRUniversité Claude Bernard Lyon 1 · FRCentre Antoine Lacassagne · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInserm · FRInstitut national de recherche en sciences et technologies du numérique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is generally accepted that carcinogenesis and aging are two biological processes, which are known to be associated. Notably, the frequency of certain cancers (including lung cancer), increases significantly with the age of patients and there is now a wealth of data showing that multiple mechanisms leading to malignant transformation and to aging are interconnected, defining the so-called common biology of aging and cancer. OncoAge, a consortium launched in 2015, brings together the multidisciplinary expertise of leading public hospital services and academic laboratories to foster the transfer of scientific knowledge rapidly acquired in the fields of cancer biology and aging into innovative medical practice and silver economy development. This is achieved through the development of shared technical platforms (for research on genome stability, (epi)genetics, biobanking, immunology, metabolism, and artificial intelligence), clinical research projects, clinical trials, and education. OncoAge focuses mainly on two pilot pathologies, which benefit from the expertise of several members, namely lung and head and neck cancers. This review outlines the broad strategic directions and key advances of OncoAge and summarizes some of the issues faced by this consortium, as well as the short- and long-term perspectives.

Indexed as

agingcancereducationelderlyoptimizationresearchwell-being

Identifiers

PMID30795607
PMCPMC6406685
OpenAlexW2917929962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.