Evidence map›Paper›PMID 30795600›Full record

ReviewGenes2019

DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in

Michele Giannattasio, Dana Branzei

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. The tomato gene Ty-6, encoding DNA polymerase delta subunit 1, confers broad resistance to Geminiviruses.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Strand Displacement Activity of PrimPol.International journal of molecular sciences · 2020
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Michele GiannattasioIFOM (Fondazione Istituto FIRC di Oncologia Molecolare), 20139 Milan, Italy. michele.giannattasio@ifom.eu.ORCID 0000-0001-7099-5718
Dana BranzeiIFOM (Fondazione Istituto FIRC di Oncologia Molecolare), 20139 Milan, Italy. dana.branzei@ifom.eu.ORCID 0000-0002-0544-4888
IFOM · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review discusses a set of experimental results that support the existence of extended strand displacement events during budding yeast lagging strand DNA synthesis. Starting from introducing the mechanisms and factors involved in leading and lagging strand DNA synthesis and some aspects of the architecture of the eukaryotic replisome, we discuss studies on bacterial, bacteriophage and viral DNA polymerases with potent strand displacement activities. We describe proposed pathways of Okazaki fragment processing via short and long flaps, with a focus on experimental results obtained in

Indexed as

DNA ReplicationDNADNA Polymerase IIISaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNADNA Polymerase IIIOkazaki fragmentsSaccharomyces cerevisiae ProteinsDNA helicasesDNA replicationflap endonucleaseslagging strand DNA synthesisOkazaki fragment processingstrand displacement DNA synthesis

Identifiers

PMID30795600
PMCPMC6409922
OpenAlexW2917347774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.