Evidence map›Paper›PMID 30795559›Full record

ArticleJournal of clinical medicine2019

Genetic Variants in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Bayesian Approach and Systematic Review.

Kwang Seob Lee, Andreas Kronbichler, Daniel Fernando Pereira Vasconcelos, Felipe Rodolfo Pereira da Silva, Younhee Ko, Yeon Su Oh, Michael Eisenhut, Peter A Merkel, David Jayne, Christopher I Amos and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Using a Network-Based Analysis Approach to Investigate the Involvement ofInternational journal of molecular sciences · 2023
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Immunopathogenesis of ANCA-Associated Vasculitis.International journal of molecular sciences · 2020
    Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 7 countries.

Kwang Seob LeeSeverance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea. kwangseob@yuhs.ac.
Andreas KronbichlerDepartment of Internal Medicine IV (Nephrology and Hypertension), Medical University Innsbruck, 6020 Innsbruck, Austria. andreas.kronbichler@i-med.ac.at.ORCID 0000-0002-2945-2946
Daniel Fernando Pereira VasconcelosLaboratory of Histological Analysis and Preparation (LAPHIS), Federal University of Piaui, Parnaiba 64202-020, Brazil. vasconcelos@ufpi.edu.br.ORCID 0000-0002-3331-452X
Felipe Rodolfo Pereira da SilvaLaboratory of Histological Analysis and Preparation (LAPHIS), Federal University of Piaui, Parnaiba 64202-020, Brazil. feliperodolfo.15@hotmail.com.ORCID 0000-0001-9224-5571
Younhee KoDivision of Biomedical Engineering, Hankuk University of Foreign Studies, Gyeonggi-do 17035, Korea. younko@hufs.ac.kr.
Yeon Su OhYonsei University College of Medicine, Seoul 03722, Korea. nasaoh@naver.com.
Michael EisenhutDepartment of Pediatrics, Luton & Dunstable University Hospital NHS Foundation Trust, Luton LU4 0DZ, UK. michael_eisenhut@yahoo.com.
Peter A MerkelDivision of Rheumatology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19146, USA. Peter.Merkel@uphs.upenn.edu.
David JayneVasculitis and Lupus Clinic, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. dj106@cam.ac.uk.ORCID 0000-0002-1712-0637
Christopher I AmosInstitute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX 77030, USA. Christopher.I.Amos@dartmouth.edu.
Katherine A SiminovitchMount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto General Research Institute and University of Toronto, Toronto, ON M5G 1X5, Canada. Katherine.Siminovitch@sinaihealthsystem.ca.
Chinar RahmattullaDepartment of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands. c.rahmattulla@lumc.nl.
Keum Hwa LeeDepartment of Pediatrics, Yonsei University College of Medicine, Seoul 03722, Korea. AZSAGM@yuhs.ac.ORCID 0000-0002-1511-9587
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seoul 03722, Korea. SHINJI@yuhs.ac.ORCID 0000-0003-2326-1820
Yonsei University · KRUniversidade Federal do Piauí · BRBaylor College of Medicine · USHankuk University of Foreign Studies · KRInnsbruck Medical University · ATLeiden University Medical Center · NLLuton and Dunstable University Hospital NHS Foundation Trust · GBMount Sinai Hospital · CAUniversity of Cambridge · GBUniversity of Pennsylvania · US

Funding

VCRC-VF FellowshipU54AR057319 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MERKEL, PETER A · 2009 to 2020
$12.5M
VASCULITIS CLINICAL RESEARCH NETWORK (VCRN): RARE DISEASEU54RR019497 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MERKEL, PETER A · 2003 to 2008
$6.1M
NCRR NIH HHS U54 RR019497NCRR NIH HHS U54-RR-019497, U54-AR-057319 and R01-AR-047799NIAMS NIH HHS U54 AR057319
6 · The paper itself

Abstract

A number of genome-wide association studies (GWASs) and meta-analyses of genetic variants have been performed in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We reinterpreted previous studies using false-positive report probability (FPRP) and Bayesian false discovery probability (BFDP). This study searched publications in PubMed and Excerpta Medica Database (EMBASE) up to February 2018. Identification of noteworthy associations were analyzed using FPRP and BFDP, and data (i.e., odds ratio (OR), 95% confidence interval (CI),

Indexed as

antineutrophil cytoplasmic antibody (ANCA)genome-wide association studymeta-analysismyeloperoxidaseproteinase 3single nucleotide polymorphismvasculitis

Identifiers

PMID30795559
PMCPMC6406345
OpenAlexW2916101236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.