ArticlePloS one2019
Big data and analysis of risk factors for gallbladder disease in the young generation of Korea.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- Gallbladder disease diagnosis from ultrasound using squeeze-and-excitation capsule network with convolutional bidirectional long short-term memory.Scientific reports · 2026Article
- Long-term weight change patterns in American adulthood in relation to gallstones: evidence from NHANES.BMC gastroenterology · 2025Article
- MiR-33 as a novel diagnostic biomarker for distinguishing cholesterol from adenomatous polyps: a case-control study.Hereditas · 2025Article
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- Burden and risk factors for gallbladder and biliary tract diseases in China from 1990 to 2021 and burden predictions of risk factors for the next 15 years.Frontiers in medicine · 2025Article
- Gallbladder dysfunction caused by MYPT1 ablation triggers cholestasis-induced hepatic fibrosis in mice.Hepatology communications · 2024Article
- Review
- Comparison of Triglyceride-Glucose Index between Patients with Gallstone and Healthy Individuals.Iranian journal of public health · 2024Article
- Global, regional, and national burden of gallbladder and biliary diseases from 1990 to 2019.World journal of gastrointestinal surgery · 2023Article
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- Evidence-based clinical practice guidelines for cholelithiasis 2021.Journal of gastroenterology · 2023Review
- Effect of nicotine on cholesterol gallstone formation in C57BL/6J mice fed on a lithogenic diet.Experimental and therapeutic medicine · 2023Article
- Article
- Chronological trends in patients undergoing cholecystectomy in Korea: a nationwide health insurance claims study.Annals of surgical treatment and research · 2022Article
- The increasing incidence and high body mass index-related burden of gallbladder and biliary diseases-A results from global burden of disease study 2019.Frontiers in medicine · 2022Article
- Article
- Obesity and Gallstones.Visceral medicine · 2021Review
- An overview on possible links between aflatoxin BMycotoxin research · 2021Review
- Risk factors for cholesterol polyp formation in the gallbladder are closely related to lipid metabolism.Lipids in health and disease · 2021Article
- Gallbladder Polyps Increase the Risk of Ischaemic Heart Disease Among Korean Adults.Frontiers in medicine · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background/purposeFew studies have examined the risk factors for gallbladder (GB) disease in young adults. This study aimed to evaluate risk factors for GB disease in young adults based on big data in Korea.
methodsAll participants underwent routine checkup at the Korea Medical Institute from June 2014 to May 2015. After excluding 677 individuals with missing information in records, 724,114 individuals (435,635 men, 288,479 women) were finally included. The definition of abnormal GB finding included stones, sludge, polyps, and adenomyomatosis detected using ultrasonography. All statistical analyses were performed using SAS software version 9.2.
resultsOverall, 27,130 (17.5%) individuals were diagnosed as having abnormal GB finding in the young age group (N = 154,463, aged 20-39 years). In men, significant differences in low-density lipoprotein (LDL) and cholesterol levels were observed between the abnormal GB finding group and normal GB group (p < 0.05). In women, a significant difference in smoking history was noted between the abnormal GB finding group and normal GB group (p < 0.05). The prevalence rate of GB stones was 1.9% (27,979/154,463) in the young age group. High body mass index (BMI), large thigh circumference, and low high-density lipoprotein (HDL) level in women and low HDL level in men were independent risk factors for the presence of GB stones (p < 0.05).
conclusionIn this study, obesity-related factors (BMI, waist size, thigh circumference, and cholesterol, LDL, and HDL levels) correlated with GB disease in the young generation of Korea.
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