ArticleThe Laryngoscope2019
3D-printed, externally-implanted, bioresorbable airway splints for severe tracheobronchomalacia.
Article in The Laryngoscope, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 93 citations in OpenAlex.
- Three-Dimensional Printing in Dentistry: Evolution, Technologies, and Clinical Application.Polymers · 2026Review
- A Novel Approach for Tetralogy of Fallot-Absent Pulmonary Valve Using Bioresorbable Airway Splints.Pediatric cardiology · 2025Article
- Diagnosis, Treatment, and Follow-Up of Tracheo/Bronchomalacia in Children: The Italian Multicenter Experience.Children (Basel, Switzerland) · 2025Article
- Investigation of the biodegradation kinetics and associated mechanical properties of 3D-printed polycaprolactone during long-term preclinical testing.Biomaterials · 2025Article
- Review
- Tissue-Engineered Tracheal Reconstruction.Biomimetics (Basel, Switzerland) · 2025Review
- Feasibility Assessment of 3D Printing-Based Tubular Tissue Flap in a Porcine Model for Long Segmental Tracheal Reconstruction.Tissue engineering and regenerative medicine · 2025Article
- Degradation and Fatigue Behavior of 3D-Printed Bioresorbable Tracheal Splints.Journal of biomedical materials research. Part B, Applied biomaterials · 2024Article
- Setting up a biomodeling, virtual planning, and three-dimensional printing service in Uruguay.Pediatric radiology · 2024Review
- 3D Bioprinting in Otolaryngology: A Review.Advanced healthcare materials · 2023Review
- Multidisciplinary approach to vascular rings and vascular-related aerodigestive compression: a clinical practice review.Translational pediatrics · 2023Review
- Current Status and Future Outlook of Additive Manufacturing Technologies for the Reconstruction of the Trachea.Journal of functional biomaterials · 2023Review
- Bioengineering and Clinical Translation of Human Lung and its Components.Advanced biology · 2023Review
- Novel Therapy for Acquired Tracheomalacia with a Tissue-Engineered Extraluminal Tracheal Splint and Autologous Mesenchymal-Derived Chondrocytes.International archives of otorhinolaryngology · 2023Article
- Successful application of the innovation process to a case of Floyd Type I tracheal agenesis.Surgery open science · 2023Article
- Development of tissue-engineered tracheal scaffold with refined mechanical properties and vascularisation for tracheal regeneration.Frontiers in bioengineering and biotechnology · 2023Article
- Advantages of FDM and gamma irradiation to manufacture personalized medical devices for airway obstructions.Frontiers in bioengineering and biotechnology · 2023Article
- 3D Printing in Otolaryngology Surgery: Descriptive Review of Literature to Define the State of the Art.Healthcare (Basel, Switzerland) · 2022Review
- 3D Approaches in Complex CHD: Where Are We? Funny Printing and Beautiful Images, or a Useful Tool?Journal of cardiovascular development and disease · 2022Review
- Long-term outcomes in children undergoing vascular ring division: a multi-institution experience.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
objectives/hypothesisTo report the clinical safety and efficacy of three-dimensional (3D)-printed, patient-specific, bioresorbable airway splints in a cohort of critically ill children with severe tracheobronchomalacia. STUDY
designCase series.
methodsFrom 2012 to 2018, 15 subjects received 29 splints on their trachea, right and/or left mainstem bronchi. The median age at implantation was 8 months (range, 3-25 months). Nine children were female. Five subjects had a history of extracorporeal membrane oxygenation (ECMO), and 11 required continuous sedation, six of whom required paralytics to maintain adequate ventilation. Thirteen were chronically hospitalized, unable to be discharged, and seven were hospitalized their entire lives. At the time of splint implantation, one subject required ECMO, one required positive airway pressure, and 13 subjects were tracheostomy and ventilator dependent, requiring a median positive end-expiratory pressure (PEEP) of 14 cm H
resultsAt the time of discharge from our institution, at a median of 28 days postimplantation (range, 10-56 days), the subject on ECMO was weaned from extracorporeal support, and the subjects who were ventilated via tracheostomy had a median change in PEEP (discharge-baseline) of -2.5 cm H
conclusionsThis case series demonstrates the initial clinical efficacy of the 3D-printed bioresorbable airway splint device in a cohort of critically ill children with severe tracheobronchomalacia. LEVEL OF EVIDENCE: 4 Laryngoscope, 129:1763-1771, 2019.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.