ArticleeLife2019
Panton-Valentine leucocidin is the key determinant of
Open access · goldAbstract read
In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 81 citations in OpenAlex.
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- Pathogen virulence and host response: A systematic review of severe illness in childhood musculoskeletal infection.Journal of clinical orthopaedics and trauma · 2026Review
- Primary Pyomyositis of the Adductor and Pectineus Muscle in Patients With Uncontrolled Diabetes: Report of Two Cases.Case reports in orthopedics · 2026Article
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- Machine learning and statistical inference in microbial population genomics.Genome biology · 2025Review
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- Genome-based model for differentiating between infection and carriageMicrobiology spectrum · 2024Article
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- Combined reference-free and multi-reference based GWAS uncover cryptic variation underlying rapid adaptation in a fungal plant pathogen.PLoS pathogens · 2023Article
- The bacterial genetic determinants of Escherichia coli capacity to cause bloodstream infections in humans.PLoS genetics · 2023Article
- Staphylococcus aureus host interactions and adaptation.Nature reviews. Microbiology · 2023Review
- Research article network analysis of polymicrobial chronic wound infections in Masanga, Sierra Leone.BMC infectious diseases · 2023Article
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- Staphylococcus aureus populations from the gut and the blood are not distinguished by virulence traits-a critical role of host barrier integrity.Microbiome · 2022Article
- Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature.Nature communications · 2022Article
- Prophage-encoded immune evasion factors are critical forCell genomics · 2022Article
- Neutralization of the Staphylococcus aureus Panton-Valentine leukocidin by African and Caucasian sera.BMC microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 8 institutions in 5 countries.
Bernadette C YoungNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0001-6071-6770
Sarah G EarleNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0002-0738-7557
Sona SoengCambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
Poda SarCambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
Varun KumarDepartment of Pediatrics, East Tennessee State University Quillen College of Medicine, Johnson City, United States.
Songly HorCambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
Vuthy SarCambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
Rachel BousfieldDepartment of Infectious Diseases, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Nicholas D SandersonNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Leanne BarkerNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Nicole StoesserNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Katherine Rw EmaryNIHR Oxford Biomedical Research Centre, Infection Theme, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.
Christopher M ParryClinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.ORCID 0000-0001-7563-7282
Emma K NickersonDepartment of Infectious Diseases, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Paul TurnerCambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.ORCID 0000-0002-1013-7815
Rory BowdenWellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-8596-0366
Derrick W CrookNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0002-0590-2850
David H WyllieNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Nicholas Pj DayCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Daniel J WilsonNuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0002-0940-3311
Catrin E MooreCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-8639-9846
John Radcliffe Hospital · GBAngkor Hospital for Children · KHCambridge University Hospitals NHS Foundation Trust · GBCentre for Human Genetics · GBEast Tennessee State University · USLiverpool School of Tropical Medicine · GBMahidol University · THUniversity of Oxford · GB
Funding
Royal Society 101237/Z/13/ZSeventh Framework Programme 601783University Of Oxford MRF/MT2015/2180Wellcome 089275/H/09/ZWellcome 089275/Z/09/ZWellcome 090532/Z/09/ZWellcome Trust
Abstract
Pyomyositis is a severe bacterial infection of skeletal muscle, commonly affecting children in tropical regions, predominantly caused by
Indexed as
Bacterial ToxinsCambodiaExotoxinsGenome-Wide Association StudyHumansLeukocidinsPyomyositisStaphylococcal InfectionsStaphylococcus aureusVirulence FactorsBacterial ToxinsExotoxinsLeukocidinsPanton-Valentine leukocidinVirulence FactorsCambodiageneticsgenome-wide association studygenomicsinfectious diseasemicrobiologypyomyositisStaphylococcus aureus
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.