ArticleBioMedicine2019
In vitro antioxidant and antinociceptive properties of Porphyra vietnamensis.
Article in BioMedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Unravelling the photoprotective effects of freshwater alga Nostoc commune Vaucher ex Bornet et Flahault against ultraviolet radiations.Environmental science and pollution research international · 2022Article
- Article
- Development of broad spectrum mycosporine loaded sunscreen formulation from Ulva fasciata delile.BioMedicine · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent investigation explores the anti-oxidant and antinociceptive potential of edible seaweed namely Porphyra vietnamensis.
methodsRadical scavenging and antinociceptive potential of ethanolic (EE), aqueous (AE), acetone (ACE) and chloroform (CE) fractions were determined using various models and assays. Writhing, formalin, hot plate, acetic acid induce response models were performed to determine antinociceptive activity whereas different assays have been used to determine antioxidant potential.
resultsAmong the various fractions, ACE showed maximum biological activity. In DPPH assay half maximal inhibitory concentration (IC50) was found to be 0.470 ug/ml (DPPH assay), 0.381 jug/m/ (H2O2 assay), 0.470 ug/ml (super oxide assay), 0.591ug/ml (lipid peroxidation) and 0.430 ug/ml (nitric oxide assay). However, comparatively the TPC was more in EE (977.0 mg GAE/gm DW).
conclusionIt was concluded that acetone fraction of Porphyra showed marked antinociceptive and antioxidant activities, however pharmacological and chemical investigations are required to identify principle compounds responsible for activities and characterize their respective mechanism(s) for respective actions.
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Registered trials
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