ArticleJournal of veterinary internal medicine2019
Prevalence, distribution, and clinical characteristics of hemangiosarcoma-associated skeletal muscle metastases in 61 dogs: A whole body computed tomographic study.
Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- A case of canine urothelial carcinoma of the urinary bladder with skull and skeletal metastases.Australian veterinary journal · 2026Article
- Frequency, distribution, and prognostic impact of metastatic site in dogs with splenic hemangiosarcoma.Journal of veterinary internal medicine · 2026Article
- Clinical features and imaging findings for a mediastinal hemangiosarcoma in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2026Article
- The Usefulness of Extemporaneous Cytological Examination in Imaging-Guided Biopsies.Animals : an open access journal from MDPI · 2025Article
- Primary Prostatic Carcinoma with Metastasis to Epaxial Muscles and Myocardium in a Dog.Veterinary sciences · 2025Article
- Low prevalence of hemoperitoneum recurrence in dogs following splenectomy for benign splenic tumors.Frontiers in veterinary science · 2025Article
- Hemorrhagic muscular metastasis of primary splenic hemangiosarcoma in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
- Computed Tomographic Findings in Dogs with Hepatic Bacterial Parenchymal Infection and Abscessation.Animals : an open access journal from MDPI · 2024Article
- Prognostic value of tumour-related factors associated with canine retroperitoneal hemangiosarcoma in comparison with other anatomic presentations: A retrospective observational study.Veterinary medicine and science · 2024Article
- Molecular Profile of Canine Hemangiosarcoma and Potential Novel Therapeutic Targets.Veterinary sciences · 2023Review
- Review
- Skeletal muscle dissemination in a dog with T-cell lymphoma.Veterinary medicine and science · 2023Article
- Assessing the Risk of Nodal Metastases in Canine Integumentary Mast Cell Tumors: Is Sentinel Lymph Node Biopsy Always Necessary?Animals : an open access journal from MDPI · 2021Article
- Retrobulbar and Tongue Base Pyogranulomatous Myositis Resulting in Strabismus in a Dog: Case Report.Frontiers in veterinary science · 2020Article
- Prevalence, distribution, and clinical characteristics of hemangiosarcoma-associated skeletal muscle metastases in 61 dogs: A whole body computed tomographic study.Journal of veterinary internal medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSkeletal muscle metastases (SMMs) have been described sporadically in canine oncology. HYPOTHESIS/
objectivesTo determine the prevalence, localization, and clinical signs of SMMs associated with hemangiosarcoma (HSA) in a population of dogs presented for whole body computed tomography (CT). ANIMALS: Dogs with a histologically confirmed HSA and a tissue core specimen or fine needle aspirate of suspected metastatic lesions were included in the study.
methodsRetrospective study. Dogs with a final diagnosis of visceral or muscular HSA that underwent whole body CT scan were enrolled in the study. Final diagnosis of primary tumor and SMMs was reached by histology, cytology, or both. Signalment, clinical signs, localization of the primary lesion, and metastases characteristics were reviewed.
resultsSixty-one dogs met the inclusion criteria. Skeletal muscle metastases were detected in 15 dogs (24.6%) and all of these dogs had also metastases in ≥1 sites. Presence of SMMs was significantly higher in males but was not significantly related to age, neuter status, breed, localization, and dimensions of the primary tumor. Nine of 15 (60.0%) dogs with SMMs showed lameness or reluctance to move whereas these signs were not recorded in any of the 42 dogs without SMMs (P < .001). CONCLUSION AND CLINICAL IMPORTANCE: Prevalence of SMMs in our population of dogs with HSA was higher in comparison to previous studies in the human and veterinary medical literature. Whole body CT is recommended for staging of dogs with HSA, because SMMs could be missed by clinical examination and traditional diagnostic imaging modalities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.