ArticleJournal of anatomy2019
Trabecular architecture of the great ape and human femoral head.
Article in Journal of anatomy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 32 citations in OpenAlex.
- Variation in trabecular bone microarchitecture across rhesus macaque (Macaca mulatta) load-bearing joints.Journal of anatomy · 2026Article
- How do forelimb long bones adapt in rhinoceroses? An in-depth examination of their microanatomy.Journal of anatomy · 2026Article
- SwartkransProceedings of the National Academy of Sciences of the United States of America · 2026Article
- A 50-year perspective on the use and potential of artiodactyl calcanei in bone adaptation studies.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Locomotor signals in the trabecular structure of the hominoid clavicle.Journal of anatomy · 2025Article
- New insights on femoral head trabecular bone directionality in elderly humans using a micro-CT-based analysis.Scientific reports · 2025Article
- Trabecular Architecture of the Proximal Tibia in Extant Hominids.American journal of biological anthropology · 2025Article
- Trabecular architecture of the distal femur in extant hominids.Journal of anatomy · 2024Article
- Identification of functionally related adaptations in the trabecular network of the proximal femur and tibia of a bipedally trained Japanese macaque.Anthropological science : journal of the Anthropological Society of Nippon = Jinruigaku zasshi · 2024Article
- A computational framework for canonical holistic morphometric analysis of trabecular bone.Scientific reports · 2022Article
- Cortical and trabecular bone structure of the hominoid capitate.Journal of anatomy · 2021Article
- Novel strategies for the characterization of cancellous bone morphology: Virtual isolation and analysis.American journal of physical anthropology · 2021Article
- Locomotory behaviour of early tetrapods from Blue Beach, Nova Scotia, revealed by novel microanatomical analysis.Royal Society open science · 2021Article
- Article
- Evidence for habitual climbing in a Pleistocene hominin in South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies of femoral trabecular structure have shown that the orientation and volume of bone are associated with variation in loading and could be informative about individual joint positioning during locomotion. In this study, we analyse for the first time trabecular bone patterns throughout the femoral head using a whole-epiphysis approach to investigate how potential trabecular variation in humans and great apes relates to differences in locomotor modes. Trabecular architecture was analysed using microCT scans of Pan troglodytes (n = 20), Gorilla gorilla (n = 14), Pongo sp. (n = 5) and Homo sapiens (n = 12) in medtool 4.1. Our results revealed differences in bone volume fraction (BV/TV) distribution patterns, as well as overall trabecular parameters of the femoral head between great apes and humans. Pan and Gorilla showed two regions of high BV/TV in the femoral head, consistent with hip posture and loading during two discrete locomotor modes: knuckle-walking and climbing. Most Pongo specimens also displayed two regions of high BV/TV, but these regions were less discrete and there was more variability across the sample. In contrast, Homo showed only one main region of high BV/TV in the femoral head and had the lowest BV/TV, as well as the most anisotropic trabeculae. The Homo trabecular structure is consistent with stereotypical loading with a more extended hip compared with great apes, which is characteristic of modern human bipedalism. Our results suggest that holistic evaluations of femoral head trabecular architecture can reveal previously undetected patterns linked to locomotor behaviour in extant apes and can provide further insight into hip joint loading in fossil hominins and other primates.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.