Evidence map›Paper›PMID 30793155›Full record

ArticleInflammatory bowel diseases2019

A Cross-Sectional Study on Malnutrition in Inflammatory Bowel Disease: Is There a Difference Based on Pediatric or Adult Age Grouping?

Valérie Marcil, Emile Levy, Devendra Amre, Alain Bitton, Ana Maria Guilhon de Araújo Sant'Anna, Andrew Szilagy, Daniel Sinnett, Ernest G Seidman

Erratum issuedOpen access · bronzeAbstract readComparative Study
In one paragraph

Article in Inflammatory bowel diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. [Analysis of nutritional status before and after different induction therapies in children with Crohn's disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
  5. [Clinical characteristics and nutritional status of children with Crohn's disease and risk factors for malnutrition].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Valérie MarcilIBD Research Group, McGill University Health Center, Montreal, Quebec, Canada; Research Centre, Sainte-Justine UHC.
Emile LevyDepartment of Nutrition, Université de Montréal, Montreal, Quebec, Canada.
Devendra AmrePediatrics, Université de Montréal, Montreal, Quebec, Canada.
Alain BittonIBD Research Group, McGill University Health Center, Montreal, Quebec, Canada; Research Centre, Sainte-Justine UHC.
Ana Maria Guilhon de Araújo Sant'AnnaIBD Research Group, McGill University Health Center, Montreal, Quebec, Canada; Research Centre, Sainte-Justine UHC.
Andrew SzilagyIBD Research Group, McGill University Health Center, Montreal, Quebec, Canada; Research Centre, Sainte-Justine UHC.
Daniel SinnettPediatrics, Université de Montréal, Montreal, Quebec, Canada.
Ernest G SeidmanIBD Research Group, McGill University Health Center, Montreal, Quebec, Canada; Research Centre, Sainte-Justine UHC.
McGill University Health Centre · CAUniversité de Montréal · CACentre Hospitalier Universitaire Sainte-Justine · CA

Funding

CIHR CTP-82942
6 · The paper itself

Abstract

backgroundMalnutrition, commonly observed in inflammatory bowel disease (IBD), is associated with increased morbidity and mortality and is attributed to multiple causes. The added energy costs of growth in the child and adolescent with IBD are an additional risk factor.

methodsThe aim of the study was to perform a cross-sectional comparison of nutritional parameters in IBD between pediatric and adult cases.

resultsWe found that prevalence of undernutrition (low body mass index) and hypoalbuminemia was not different in pediatric, compared with adult patients. Anemia and iron deficiency were more often observed in pediatric subjects, compared with adults (59.1% vs 36.9%, respectively, P < 0.0001; and 37.9% vs 25.3%, P < 0.002). Vitamin B12 deficiency was significantly less common in the pediatric than in the adult group (5.4% vs 19.4%, P < 0.0001). Elevated C-reactive protein was more frequent in pediatric compared with adult cases (49.8% vs 38.4%, P < 0.01).

conclusionsPatients with active Crohn's disease were more likely to be undernourished in both pediatric and adult populations. In both groups, predicators of undernutrition included low albumin levels (odds ratio [OR], 2.53; P < 0.006) and active disease (OR, 1.99; P < 0.03). Our results call for close surveillance of nutritional status for IBD patients, regardless of age.

Indexed as

AdolescentAdultAnemia, Iron-DeficiencyCanadaChildChild, PreschoolCross-Sectional StudiesFemaleFollow-Up StudiesHumansHypoalbuminemiaInfantInfant, NewbornInflammatory Bowel DiseasesMaleMalnutritionanemiaCrohn’s diseaseinflammatory bowel diseasemalnutritionulcerative colitis

Identifiers

PMID30793155
PMCPMC6635818
OpenAlexW2915560844

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.