Evidence map›Paper›PMID 30793116›Full record

ArticleJournal of cancer research forecast2018

Cell Specific Matrix Metalloproteinase-1 Regulates Lung Metastasis Synergistically with Smoke Exposure.

A Morishita, A Gerber, C-H Gow, T Zelonina, K Chada, J D'Armiento

Open access · greenAbstract read
In one paragraph

Article in Journal of cancer research forecast, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  7. [Alkaline processing of cantharidin can significanty improve the antitumor activity of cantharidin].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

A MorishitaKagawa Daigaku, Gastroenterology and Neurology, 1-1 Saiwaicho, Takamatsu, Kagawa, JP 760-8523, Japan.
A GerberDepartments of Medicine, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.
C-H GowDepartments of Medicine, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.
T ZeloninaDepartments of Medicine, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.
K ChadaDepartment of Biochemistry and Molecular Biology, Rutgers-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, New Jersey 08854, USA.
J D'ArmientoDepartments of Medicine, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.
Columbia University · USJohnson University · USKagawa University · JP

Funding

ANESTHESIOLOGY RESEARCH TRAININGT32GM008464 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI CHARLES W EMALA, May Hua · 1992 to 2026
$6.0M
Smoke Induced Airway Injury in the LungR01HL086936 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI D'ARMIENTO, JEANINE M · 2007 to 2016
$3.7M
Inducible Macrophage Specific Gene Expression in DiseasesRC1HL100384 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI D'ARMIENTO, JEANINE M · 2009 to 2010
$969k
NHLBI NIH HHS R01 HL086936NHLBI NIH HHS RC1 HL100384NIGMS NIH HHS T32 GM008464
6 · The paper itself

Abstract

MMP1, a matrix metalloproteinase that degrades the extracellular matrix, is produced not only by cancer cells but also synthesized in stromal and inflammatory cells during tumorigenesis, invasion and lung metastasis. However, the function of MMP1 expression from host cells, especially tumor-associated macrophages (TAMs), and cells in the lung parenchyma remains to be elucidated. Here we demonstrate that

Indexed as

MacrophagesMetalloproteinaseMetastasisMMP1

Identifiers

PMID30793116
PMCPMC6380525
OpenAlexW2981239648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.