ReviewTurkish journal of emergency medicine2019
Essential pharmacologic options for acute pain management in the emergency setting.
Review in Turkish journal of emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Pain Assessment and Management in Pediatric Trauma Patients Transported to an Emergency Department: A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Acute pain management in older adults presenting to the emergency department: a clinical review.Singapore medical journal · 2026Review
- Beyond the Ladder: A 10-Domain Cognitive and Operational Toolkit to Humanise and Implement Acute Pain Guidelines at the Bedside.Pain research & management · 2026Review
- A review on gut microbiota and migraine severity: a complex relationship.Inflammopharmacology · 2026Review
- Questionable role of opioids for analgesia in renal colic and its urological interventions.BJUI compass · 2025Review
- Acute Pain Management in Peripheral Artery Disease: A Holistic, Beyond-Opioids, Individualized Multimodal Approach.Turkish journal of anaesthesiology and reanimation · 2024Review
- Novel Techniques for Musculoskeletal Pain Management after Orthopedic Surgical Procedures: A Systematic Review.Life (Basel, Switzerland) · 2023Review
- Efficacy of Sumatriptan/Placebo versus Sumatriptan/Propofol Combination in Acute Migraine; a Randomized Clinical Trial.Archives of academic emergency medicine · 2022Article
- Inhaled methoxyflurane (Penthrox) for analgesia in trauma: a systematic review protocol.Systematic reviews · 2021Article
- Comparison of Ketamine and Tramadol in Management of Acute Pain; a Systematic Review.Archives of academic emergency medicine · 2020Review
- A comparative experimental study of analgesic activity of a novel non-steroidal anti-inflammatory molecule - zaltoprofen, and a standard drug - piroxicam, using murine models.Journal of experimental pharmacology · 2019Article
- Chronic postoperative pain: ubiquitous and scarcely appraised: narrative review.Brazilian journal of anesthesiology (Elsevier)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain is the root cause for the overwhelming majority of emergency department (ED) visits worldwide. However, pain is often undertreated due to inappropriate analgesic dosing and ineffective utilization of available analgesics. It is essential for emergency providers to understand the analgesic armamentarium at their disposal and how it can be used safely and effectively to treat pain of every proportion within the emergency setting. A 'balanced analgesia' regimen may be used to treat pain while reducing the overall pharmacologic side effect profile of the combined analgesics. Channels-Enzymes-Receptors Targeted Analgesia (CERTA) is a multimodal analgesic strategy incorporating balanced analgesia by shifting from a system-based to a mechanistic-based approach to pain management that targets the physiologic pathways involved in pain signaling transmission. Targeting individual pain pathways allows for a variety of reduced-dose pharmacologic options - both opioid and non-opioid - to be used in a stepwise progression of analgesic strength as pain advances up the severity scale. By developing a familiarity with the various analgesic options at their disposal, emergency providers may formulate safe, effective, balanced analgesic combinations unique to each emergency pain presentation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.