ArticleJournal of clinical & translational endocrinology2019
Thyroid vascularization is an important ultrasonographic parameter in untreated Graves' disease patients.
Article in Journal of clinical & translational endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Case Report: Suspected Rupture of a Papillary Thyroid Tumor in a Patient With Graves' Disease Who Experienced Airway Narrowing Without Respiratory Distress.Clinical medicine insights. Case reports · 2026Article
- Qualitative and quantitative CEUS assessment for differential diagnosis in thyrotoxicosis: destruction vs. hyperfunction.Endocrine · 2025Article
- Value of two-dimensional shear wave elastography quantitative analysis for evaluation of thyroid function in first trimester pregnancy.World journal of radiology · 2025Article
- Establishing Reference Values for Thyroid Vascularity Using Ultra-Micro Angiography (UMA) Ultrasound Technology.Diagnostics (Basel, Switzerland) · 2025Article
- Near-infrared diffuse optical characterization of human thyroid using ultrasound-guided hybrid time-domain and diffuse correlation spectroscopies.Biomedical optics express · 2024Article
- Pediatric Graves' Disease: Surgical Interventions in a Single Institution - A Comprehensive Case Series.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Minor hyperthyroidism with normal levels of thyroid-stimulating hormone receptor antibodies: a case report.Journal of medicine and life · 2024Article
- Thyroid ultrasound pattern in primary hypothyroidism is similar to Graves' disease: a report of three cases.Journal of medicine and life · 2024Article
- Quantitative Diagnosis Progress of Ultrasound Imaging Technology in Thyroid Diffuse Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Usefulness of Real-Time Quantitative Microvascular Ultrasonography for Differentiation of Graves' Disease from Destructive Thyroiditis in Thyrotoxic Patients.Endocrinology and metabolism (Seoul, Korea) · 2022Observational
- Duplex Hemodynamic Parameters of Both Superior and Inferior Thyroid Arteries in Evaluation of Thyroid Hyperfunction Disorders.International journal of general medicine · 2022Article
- Study of the Associations between Color Doppler Ultrasound Grading of Hyperthyroidism and Biochemical Data on Thyroid Function.International journal of endocrinology · 2022Article
- Changes of autoantibodies and intercellular adhesion molecule-1 in patients with Graves disease after clinical treatment.American journal of translational research · 2021Article
- Heterogeneity and Dynamics of Vasculature in the Endocrine System During Aging and Disease.Frontiers in physiology · 2021Review
- The various faces of hyperthyroidism.Journal of clinical & translational endocrinology · 2020Article
- Subacute Thyroiditis is Associated withJournal of clinical medicine · 2020Article
- The Clinical Value and Variation of Antithyroid Antibodies during Pregnancy.Disease markers · 2020Review
- Eosinophil/Monocyte Ratio Combined With Serum Thyroid Hormone for Distinguishing Graves' Disease and Subacute Thyroiditis.Frontiers in endocrinology · 2020Article
- The Association of Autoantibodies in Hyperthyroid Heart Disease Combined with Pulmonary Hypertension.International journal of endocrinology · 2019Article
- The contribution of ultrasonographic findings to the prognosis of subacute thyroiditis.Archives of endocrinology and metabolismArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
Graves' disease is characterized by two sonographic features, hypoechogenicity and increased blood flow. The aim of this study was to review retrospectively ultrasound features and biochemical data of a cohort of untreated Graves' disease patients. We reviewed charts of 42 such patients, who were referred to our Endocrinology Unit from January 2013 to May 2018. One operator performed all the thyroid sonographic scans. Serum TSH, FT3, FT4 and TSH-receptor antibodies (TRAb) levels at the time of ultrasound examination were evaluated. Over a mean follow-up of 30.9 months, about one in three patients (38%) experienced at least one recurrence of hyperthyroidism (1.4 ± 0.6 recurrence per patient), either on or off antithyroid drugs. We found that thyroid vascularization correlated directly with thyroid volume and that larger thyroids tended to be more vascularized. We also found that greater vascularization was associated with marked hypoechogenicity, and greater FT4 and TRAb levels. Patients who experienced recurrence(s) had 1.7-fold higher levels of TRAb at onset. In conclusion, thyroid hypervascularization at onset of Graves' disease is an important sonographic feature.
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