Evidence map›Paper›PMID 30792868›Full record

ArticleGastroenterology report2019

Risk factors for colorectal neoplasia in patients with underlying inflammatory bowel disease: a multicenter study.

Xian-Rui Wu, Xiao-Bin Zheng, Yan Huang, Qian Cao, Hong-Jie Zhang, Ying-Lei Miao, Kai-Fang Zou, Min Chen, Fa-Ming Zhang, Qiao Mei and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Gastroenterology report, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 2 countries.

Xian-Rui WuDepartment of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Xiao-Bin ZhengDepartment of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Yan HuangGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Qian CaoDepartment of Gastroenterology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Hong-Jie ZhangDepartment of Gastroenterology, Jiangsu Province Hospital, Nanjing, China.
Ying-Lei MiaoDepartment of Gastroenterology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Kai-Fang ZouDepartment of Gastroenterology, Wuhan Union Hospital, Wuhan, China.
Min ChenDepartment of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Fa-Ming ZhangMedical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qiao MeiDepartment of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
David GonzaloDepartment of Pathology and Laboratory Medicine, University of Florida, Gainesville, FL, USA.
Daniela AllendeDepartment of Anatomic Pathology, The Cleveland Clinic Foundation, Cleveland, OH, USA.
Pin-Jin HuGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Bo ShenDepartment of Gastroenterology/Hepatology, The Cleveland Clinic Foundation, Cleveland, OH, USA.
Xiu-Li LiuDepartment of Pathology and Laboratory Medicine, University of Florida, Gainesville, FL, USA.
Ping LanDepartment of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Sixth Affiliated Hospital of Sun Yat-sen University · CNCleveland Clinic · USSun Yat-sen University · CNUniversity of Florida · USAnhui Medical University · CNJiangsu Province Hospital · CNKunming Medical University · CNSecond Affiliated Hospital of Nanjing Medical University · CNSir Run Run Shaw Hospital · CNWuhan Union Hospital · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study sought to evaluate the risk factors for the development of colitis-associated neoplasia (CAN) in Chinese patients with inflammatory bowel disease (IBD).

methodsIBD patients who developed CAN between 1999 and 2016 were identified from eight medical centers. In addition to initial pathology evaluation, a CAN diagnosis was confirmed by two expert pathologists. Patients with CAN (

resultsOf the 29 patients with CAN, 8 (27.6%) had colorectal cancer (CRC), 20 (69.0%) had a final diagnosis of low-grade dysplasia and 1 (3.4%) had high-grade dysplasia. Multivariate analysis revealed that an older age at the time of IBD diagnosis and a longer IBD duration were independent risk factors for the development of CAN, with odds ratios of 1.09 [95% confidence interval (CI): 1.04-1.14,

conclusionsOlder age at the time of IBD diagnosis and longer IBD duration were found to be associated with the development of CAN in IBD patients.

Indexed as

Colorectal neoplasiainflammatory bowel diseaserisk factor

Identifiers

PMID30792868
PMCPMC6375343
OpenAlexW2905085548

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.