Evidence map›Paper›PMID 30792853›Full record

ArticleAntimicrobial resistance and infection control2019

Phenotypic and molecular characterisations of carbapenem-resistant

Pierrette Landrie Simo Tchuinte, Mamitiana Alain Noah Rabenandrasana, Carole Kowalewicz, Volasoa Herilalaina Andrianoelina, Andriniaina Rakotondrasoa, Zafitsara Zo Andrianirina, Vincent Enouf, Elisoa Hariniaina Ratsima, Frédérique Randrianirina, Jean-Marc Collard

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. CRISPR-Based Gene Editing inPharmaceuticals (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Molecular Characterization of Carbapenem-ResistantInfection and drug resistance · 2022
    Review
  9. Antibiotic-ResistantAntibiotics (Basel, Switzerland) · 2021
    Review
  10. Genetic diversity of colistin resistance NosocomialJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
    Article
  11. Molecular Epidemiology and Clone Transmission of Carbapenem-ResistantFrontiers in cellular and infection microbiology · 2021
    Article
  12. Multidrug ResistantFrontiers in microbiology · 2021
    Article
  13. Article
  14. Mechanisms ProtectingInternational journal of molecular sciences · 2020
    Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pierrette Landrie Simo Tchuinte *1Institut Pasteur de Madagascar, Antananarivo, Madagascar.ORCID 0000-0001-8183-5314
Mamitiana Alain Noah Rabenandrasana *1Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Carole Kowalewicz1Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Volasoa Herilalaina Andrianoelina1Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Andriniaina Rakotondrasoa1Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Zafitsara Zo AndrianirinaService de Pédiatrie et Néonatologie, Centre Hospitalier de Soavinandriana, Antananarivo, Madagascar.
Vincent Enouf2Institut Pasteur, Pasteur International Bioresources network (PIBnet), Plateforme de Microbiologie Mutualisée (P2M), Paris, France.
Elisoa Hariniaina Ratsima1Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Frédérique Randrianirina1Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Jean-Marc Collard1Institut Pasteur de Madagascar, Antananarivo, Madagascar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The present study aimed to perform a deep phenotypic and genotypic analysis of 15 clinical carbapenem-resistant Methods: CRAb isolates collected from the Clinical Biology Centre of the Institut Pasteur of Madagascar, from the neonatal unit of Antananarivo military hospital, and from intensive care units of Mahajanga Androva and Antananarivo Joseph Ravoahangy Andrianavalona (HJRA) hospitals were subjected to susceptibility testing. Whole-genome sequencing allowed us to assess the presence of antibiotic-resistance determinants, insertion sequences, integrons, genomic islands and potential virulence factors in all strains. The structure of the Results: All isolates were found to be multidrug-resistant strains. Antibiotic-resistance genes against six classes of antimicrobial agents were described. The four carbapenem-resistance genes: Conclusions: This study revealed the presence of high-level carbapenem resistance in

Indexed as

Drug Resistance, Multiple, BacterialAcinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial ProteinsCarbapenemsDNA Transposable ElementsGenomic IslandsHumansIntegronsMadagascarMicrobial Sensitivity TestsPhenotypePlasmidsVirulence FactorsAnti-Bacterial AgentsBacterial ProteinsCarbapenemsDNA Transposable ElementsVirulence FactorsAcinetobacter baumanniiAntimicrobial resistanceCarbapenem-resistance

Identifiers

PMID30792853
PMCPMC6371490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.