Evidence map›Paper›PMID 30792738›Full record

ArticleInternational journal of biomedical imaging2019

Magnetic Resonance Angiography Shows Increased Arterial Blood Supply Associated with Murine Mammary Cancer.

Devkumar Mustafi, Abby Leinroth, Xiaobing Fan, Erica Markiewicz, Marta Zamora, Jeffrey Mueller, Suzanne D Conzen, Gregory S Karczmar

Open access · goldAbstract read
In one paragraph

Article in International journal of biomedical imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Devkumar MustafiDepartment of Radiology, The University of Chicago, Chicago, Illinois 60637, USA.ORCID 0000-0001-7826-4485
Abby LeinrothDepartment of Radiology, The University of Chicago, Chicago, Illinois 60637, USA.
Xiaobing FanDepartment of Radiology, The University of Chicago, Chicago, Illinois 60637, USA.
Erica MarkiewiczDepartment of Radiology, The University of Chicago, Chicago, Illinois 60637, USA.
Marta ZamoraDepartment of Radiology, The University of Chicago, Chicago, Illinois 60637, USA.
Jeffrey MuellerDepartment of Pathology, The University of Chicago, Chicago, Illinois 60637, USA.
Suzanne D ConzenDepartment of Medicine, Section of Hematology and Oncology, The University of Chicago, Chicago, Illinois 60637, USA.
Gregory S KarczmarDepartment of Radiology, The University of Chicago, Chicago, Illinois 60637, USA.ORCID 0000-0002-2455-5858
University of Chicago · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1M
Breast Cancer Screening with Quantitative Ultra-Fast DCEMRI and Clinical Risk AssessmentR01CA218700 · NCI · UNIVERSITY OF CHICAGO · PI KARCZMAR, GREGORY S. · 2017 to 2021
$3.0M
Assessment of Breast Cancer Risk with High Spectral and Spatial Resolution MRIR01CA167785 · NCI · UNIVERSITY OF CHICAGO · PI KARCZMAR, GREGORY S., NEWSTEAD, GILLIAN · 2013 to 2017
$2.4M
MRI of Early Non-invasive Rodent Mammary CancersR01CA133490 · NCI · UNIVERSITY OF CHICAGO · PI KARCZMAR, GREGORY S. · 2011 to 2015
$1.6M
NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA133490NCI NIH HHS R01 CA167785NCI NIH HHS R01 CA218700
6 · The paper itself

Abstract

Breast cancer is a major cause of morbidity and mortality in Western women. Tumor neoangiogenesis, the formation of new blood vessels from pre-existing ones, may be used as a prognostic marker for cancer progression. Clinical practice uses dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) to detect cancers based on increased blood flow and capillary permeability. However, DCE-MRI requires repeated injections of contrast media. Therefore we explored the use of noninvasive time-of-flight (TOF) MR angiography for serial studies of mouse mammary glands to measure the number and size of arteries feeding mammary glands with and without cancer. Virgin female C3(1) SV40 TAg mice (n=9), aged 18-20 weeks, were imaged on a 9.4 Tesla small animal scanner. Multislice T

Identifiers

PMID30792738
PMCPMC6354161
OpenAlexW2910304939

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.