Evidence map›Paper›PMID 30792721›Full record

ArticleFrontiers in immunology2019

1,25-Dihydroxyvitamin D3 Ameliorates Collagen-Induced Arthritis via Suppression of Th17 Cells Through miR-124 Mediated Inhibition of IL-6 Signaling.

Li Zhou, Julie Wang, Jingren Li, Ting Li, Yanming Chen, Rayford R June, Song Guo Zheng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

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  12. Dry Eye Disease: What Is the Role of Vitamin D?International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Li ZhouDivision of Endocrinology, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Julie WangDivision of Rheumatology, College of Medicine, The Pennsylvania State University, Hershey, PA, United States.
Jingren LiDivision of Endocrinology, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Ting LiDivision of Endocrinology, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yanming ChenDivision of Endocrinology, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Rayford R JuneDivision of Rheumatology, College of Medicine, The Pennsylvania State University, Hershey, PA, United States.
Song Guo ZhengDivision of Rheumatology, College of Medicine, The Pennsylvania State University, Hershey, PA, United States.
Third Affiliated Hospital of Sun Yat-sen University · CNPennsylvania State University · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Institutional Career Development CoreKL2TR002015 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VAN SCOY, LAUREN JODI · 2016 to 2025
$7.8M
Therapeutic immunoregulation mediated by TGF-??-induced iTregs in autoimmune arthR01AR059103 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JARJOUR, WAEL N · 2010 to 2020
$3.9M
NCATS NIH HHS KL2 TR002015NCATS NIH HHS UL1 TR002014NIAMS NIH HHS R01 AR059103
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArthritis, ExperimentalDisease Models, AnimalGene Expression RegulationInterleukin-6MiceMice, TransgenicMicroRNAsRNA InterferenceSignal TransductionTh17 CellsT-Lymphocyte SubsetsVitamin DX-Ray Microtomographydihydroxy-vitamin D3Interleukin-6MicroRNAsMirn124 microRNA, mouseVitamin DIL-6RmiRNA-124rheumatoid arthritisTh17 cellsvitamin D

Identifiers

PMID30792721
PMCPMC6374300
OpenAlexW2914604997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.