Evidence map›Paper›PMID 30792267›Full record

ArticleGenetics2019

A Multivariate Genome-Wide Association Study of Wing Shape in

William Pitchers, Jessica Nye, Eladio J Márquez, Alycia Kowalski, Ian Dworkin, David Houle

Abstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Utilizing developmental dynamics for evolutionary prediction and control.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Taking quantitative genomics into the wild.Proceedings. Biological sciences · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Correlational selection in the age of genomics.Nature ecology & evolution · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William PitchersDepartment of Integrative Biology, Program in Ecology, Evolutionary Biology and Behavior, Michigan State University, East Lansing, Michigan.ORCID 0000-0003-0385-5939
Jessica NyeDepartment of Biological Science, Florida State University, Tallahassee, Florida.ORCID 0000-0001-6957-0931
Eladio J MárquezDepartment of Biological Science, Florida State University, Tallahassee, Florida.
Alycia KowalskiDepartment of Integrative Biology, Program in Ecology, Evolutionary Biology and Behavior, Michigan State University, East Lansing, Michigan.
Ian DworkinDepartment of Integrative Biology, Program in Ecology, Evolutionary Biology and Behavior, Michigan State University, East Lansing, Michigan dhoule@bio.fsu.edu dworkin@mcmaster.ca.ORCID 0000-0002-2874-287X
David HouleDepartment of Biological Science, Florida State University, Tallahassee, Florida dhoule@bio.fsu.edu dworkin@mcmaster.ca.ORCID 0000-0002-8095-3156

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Building, understanding and applying a dictionary of genetic effectsR01GM094424 · NIGMS · FLORIDA STATE UNIVERSITY · PI DWORKIN, IAN MICHAEL, HOULE, DAVID · 2010 to 2013
$1.6M
NIGMS NIH HHS R01 GM094424NIH HHS P40 OD018537
6 · The paper itself

Abstract

Due to the complexity of genotype-phenotype relationships, simultaneous analyses of genomic associations with multiple traits will be more powerful and informative than a series of univariate analyses. However, in most cases, studies of genotype-phenotype relationships have been analyzed only one trait at a time. Here, we report the results of a fully integrated multivariate genome-wide association analysis of the shape of the

Indexed as

Polymorphism, Single NucleotideAnimalsDrosophila melanogasterDrosophila ProteinsGenome-Wide Association StudyReference StandardsWings, AnimalDrosophila Proteinsdevelopmental geneticsDrosophila winggenome-wide association analysisGP mapmultivariate GWASphenomics

Identifiers

PMID30792267
PMCPMC6456314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.