Evidence map›Paper›PMID 30792186›Full record

ArticleThe Journal of experimental medicine2019

Human colon organoids reveal distinct physiologic and oncogenic Wnt responses.

Birgitta E Michels, Mohammed H Mosa, Britta M Grebbin, Diego Yepes, Tahmineh Darvishi, Johannes Hausmann, Henning Urlaub, Stefan Zeuzem, Hans M Kvasnicka, Thomas Oellerich and 1 more

Abstract read
In one paragraph

Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. CRISPR/Cas9: a powerful tool in colorectal cancer research.Journal of experimental & clinical cancer research : CR · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Birgitta E MichelsGerman Cancer Consortium, Germany.
Mohammed H MosaGerman Cancer Consortium, Germany.ORCID 0000-0002-8950-8470
Britta M GrebbinGerman Cancer Consortium, Germany.ORCID 0000-0002-7371-8924
Diego YepesGerman Cancer Consortium, Germany.
Tahmineh DarvishiGerman Cancer Consortium, Germany.
Johannes HausmannDepartment of Internal Medicine I, Gastroenterology, Goethe University, Frankfurt am Main, Germany.
Henning UrlaubMax Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Stefan ZeuzemDepartment of Internal Medicine I, Gastroenterology, Goethe University, Frankfurt am Main, Germany.
Hans M KvasnickaSenckenberg Institute of Pathology, Goethe University, Frankfurt am Main, Germany.
Thomas OellerichGerman Cancer Consortium, Germany.
Henner F FarinGerman Cancer Consortium, Germany farin@gsh.uni-frankfurt.de.ORCID 0000-0003-1558-5366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constitutive Wnt activation upon loss of

Indexed as

AdenomaAdenomatous Polyposis Coli ProteinBiomarkers, TumorColonColonic NeoplasmsGene Expression RegulationGene Knockout TechniquesHumansKaplan-Meier EstimateOrganoidsWnt Signaling PathwayAdenomatous Polyposis Coli ProteinAPC protein, humanBiomarkers, Tumor

Identifiers

PMID30792186
PMCPMC6400532

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.