Evidence map›Paper›PMID 30791742›Full record

ArticleIntegrative cancer therapies

Chinese Herbal Medicine Effectively Prolongs the Overall Survival of Pancreatic Cancer Patients: A Case Series.

Wendy Wong, Bing Zhong Chen, Allyson Kin Yan Lee, Adrian Ho Cheung Chan, Justin Che Yuen Wu, Zhixiu Lin

Open access · goldAbstract read
In one paragraph

Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Frontiers in oncology · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. The Effects of Plumbagin on Pancreatic Cancer: A Mechanistic Network Pharmacology Approach.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wendy Wong1 The Chinese University of Hong Kong, Shatin New Town, Hong Kong.ORCID 0000-0001-8731-0498
Bing Zhong Chen1 The Chinese University of Hong Kong, Shatin New Town, Hong Kong.
Allyson Kin Yan Lee1 The Chinese University of Hong Kong, Shatin New Town, Hong Kong.
Adrian Ho Cheung Chan1 The Chinese University of Hong Kong, Shatin New Town, Hong Kong.
Justin Che Yuen Wu1 The Chinese University of Hong Kong, Shatin New Town, Hong Kong.
Zhixiu Lin1 The Chinese University of Hong Kong, Shatin New Town, Hong Kong.
Chinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPancreatic cancer has the lowest survival rate of all cancers (4%), and it accounts for 1.9% of new cancer cases in Hong Kong. Combined treatment with Chinese herbal medicine (CHM) and Western medicine has yielded promising results, leading to improved prognosis and overall survival. This retrospective case series aimed to illustrate the improved survival and quality of life outcomes of pancreatic cancer patients administered CHM based on traditional Chinese medicine theory.

methodsTo investigate the effectiveness of CHM in prolonging overall survival, 182 patients diagnosed with pancreatic cancer who received CHM treatment were observed from 2005 to 2015.

resultsOne hundred eighty-two pancreatic cancer patients were treated with CHM; 21 patients died. The mean and median survival of these patients were 29.6 and 15.2 months, respectively; the 1-year survival rate was 76% (range = 4 months to 9 years). These results are better than those reported in patients treated with Western medicine, suggesting the need for further study of CHM.

conclusionA superior clinical outcome may be obtained with CHM treatment. The case series illustrates the potential benefits and safety issues of CHM in pancreatic cancer patients that could be relevant for developing strategies to increase individualization of pancreatic cancer treatment and improve survival. This study may facilitate interprofessional communication and improved clinical management of pancreatic cancer patients.

Indexed as

AdultAgedDrugs, Chinese HerbalFemaleHumansMaleMedicine, Chinese TraditionalMiddle AgedNeoplasm StagingPancreatic NeoplasmsPrognosisQuality of LifeRetrospective StudiesSurvival RateDrugs, Chinese Herbalcase seriesherb-drug interactionsafety

Identifiers

PMID30791742
PMCPMC6432679
OpenAlexW2913126496

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.