Evidence map›Paper›PMID 30791681›Full record

ArticleThe Korean journal of internal medicine2020

Combined effect of hepatic venous pressure gradient and liver stiffness on long-term mortality in patients with cirrhosis.

Jae Gon Lee, Joo Hyun Sohn, Jae Yoon Jeong, Tae Yeob Kim, Sun Min Kim, Young Seo Cho, Yongsoo Kim

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Article in The Korean journal of internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jae Gon LeeDepartment of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.
Joo Hyun SohnDepartment of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.
Jae Yoon JeongDepartment of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.
Tae Yeob KimDepartment of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.
Sun Min KimDepartment of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.
Young Seo ChoDepartment of Radiology, Hanyang University Guri Hospital, Guri, Korea.
Yongsoo KimDepartment of Radiology, Hanyang University Guri Hospital, Guri, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsBoth hepatic venous pressure gradient (HVPG) and liver stiffness (LS) are useful tools for predicting mortality in patients with cirrhosis. We investigated the combined effect of HVPG and LS on long-term mortality in patients with cirrhosis.

methodsWe retrospectively collected data from 103 patients with cirrhosis, whose HVPG and LS were measured between November 2009 and September 2013. The patients were divided into four groups according to the results of the HVPG and LS measurements. Long-term mortality and the risk factors for mortality were analyzed.

resultsOf the 103 patients, 35 were in group 1 (low HVPG and low LS), 16 in group 2 (high HVPG and low LS), 24 in group 3 (low HVPG and high LS), and 28 in group 4 (high HVPG and high LS). Over a median follow-up of 47.3 months, 18 patients died. The mortality rate of patients in group 4 was significantly higher than in the other three groups (vs. group 1, p = 0.005; vs. group 2, p = 0.049; vs. group 3, p = 0.004), but there were no significant differences in survival between groups 1, 2, and 3. In multivariable analyses, both HVPG and LS were identified as independent risk factors for mortality (hazard ratio [HR], 1.127, p = 0.018; and HR, 1.062, p = 0.009, respectively).

conclusionIn patients with cirrhosis, those with concurrent elevation of HVPG and LS had the highest long-term mortality rates. However, when either HVPG or LS alone was elevated, mortality did not increase significantly.

Indexed as

Elasticity Imaging TechniquesHypertension, PortalHumansLiver CirrhosisPortal PressureRetrospective StudiesHepatic venous pressure gradientLiver cirrhosisLiver stiffnessMortalityShear wave elastography

Identifiers

PMID30791681
PMCPMC6960044

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.