Evidence map›Paper›PMID 30791598›Full record

ArticleToxins2019

Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents.

Wendy S Smith, David A Johnston, Suzanne E Holmes, Harrison J Wensley, Sopsamorn U Flavell, David J Flavell

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wendy S SmithThe Simon Flavell Leukaemia Research Laboratory, Southampton General Hospital, Southampton SO16 6YD, UK. WendyS@leukaemiabusters.org.uk.ORCID 0000-0002-2413-6717
David A JohnstonBiomedical Imaging Unit, University of Southampton School of Medicine, Southampton General Hospital, Southampton SO16 6YD, UK. D.A.Johnston@soton.ac.uk.
Suzanne E HolmesThe Simon Flavell Leukaemia Research Laboratory, Southampton General Hospital, Southampton SO16 6YD, UK. SuzanneH@leukaemiabusters.org.uk.
Harrison J WensleyThe Simon Flavell Leukaemia Research Laboratory, Southampton General Hospital, Southampton SO16 6YD, UK. HarrisonW@leukaemiabusters.org.uk.ORCID 0000-0002-9634-5462
Sopsamorn U FlavellThe Simon Flavell Leukaemia Research Laboratory, Southampton General Hospital, Southampton SO16 6YD, UK. BeeF@leukaemiabusters.org.uk.
David J FlavellThe Simon Flavell Leukaemia Research Laboratory, Southampton General Hospital, Southampton SO16 6YD, UK. DavidF@leukaemiabusters.org.uk.ORCID 0000-0001-7145-4737
Southampton General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triterpenoid saponins from

Indexed as

Cell Line, TumorCell SurvivalEndocytosisEndosomesHumansImmunotoxinsLeukemiaLymphomaReactive Oxygen SpeciesSaponinsSaporinsTriterpenesImmunotoxinsReactive Oxygen SpeciesSaponinsSaporinsTriterpenesaugmentationendocytosisimmunotoxinreactive oxygen speciessaponinsaporin

Identifiers

PMID30791598
PMCPMC6410249
OpenAlexW2916841226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.