Evidence map›Paper›PMID 30791592›Full record

ArticleSensors (Basel, Switzerland)2019

Automated Chemical Sensing Unit Integration for Parallel Optical Interrogation.

Ana L Hernandez, Fabian Dortu, Theo Veenstra, Paula Ciaurriz, Rafael Casquel, Iñaki Cornago, Hendrik V Horsten, Edurne Tellechea, María V Maigler, Fátima Fernández and 1 more

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ana L HernandezCentre for Biomedical Technology, Optics, Photonics and Biophotonics Laboratory, Campus Montegancedo, Universidad Politécnica de Madrid, 28223 Madrid, Spain. Ana.lopez@upm.es.
Fabian DortuMultitel, Parc Initialis 2, Rue Pierre et Marie Curie, 7000 Mons, Belgium. dortu@multitel.be.ORCID 0000-0002-3656-4620
Theo VeenstraLioniX International BV, Hengelosestraat 500, 7521AN Enschede, The Netherlands. t.t.veenstra@lionix-int.com.
Paula CiaurrizNaitec, Polígono Mocholí, Plaza Cein, 4, 31110 Noain, Spain. pciaurriz@naitec.es.
Rafael CasquelCentre for Biomedical Technology, Optics, Photonics and Biophotonics Laboratory, Campus Montegancedo, Universidad Politécnica de Madrid, 28223 Madrid, Spain. rafael.casquel@upm.es.
Iñaki CornagoNaitec, Polígono Mocholí, Plaza Cein, 4, 31110 Noain, Spain. icornago@naitec.es.
Hendrik V HorstenMultitel, Parc Initialis 2, Rue Pierre et Marie Curie, 7000 Mons, Belgium. vonhorsten@multitel.be.ORCID 0000-0003-1838-8165
Edurne TellecheaNaitec, Polígono Mocholí, Plaza Cein, 4, 31110 Noain, Spain. eteiletxea@naitec.es.
María V MaiglerBio Optical Detection, Centro de empresas de la Universidad Politécnica de Madrid, Pozuelo de Alarcón, 28223 Madrid, Spain. mavi.maigler@upm.es.
Fátima FernándezNaitec, Polígono Mocholí, Plaza Cein, 4, 31110 Noain, Spain. fatima.fernandez.santos@gmail.com.
Miguel HolgadoCentre for Biomedical Technology, Optics, Photonics and Biophotonics Laboratory, Campus Montegancedo, Universidad Politécnica de Madrid, 28223 Madrid, Spain. m.holgado@upm.es.

Funding

European Commission FP7-OCEAN-2013-614057Ministerio de Economía, Industria y Competitividad, Gobierno de España TEC2012-31145, RTC-2015-3273-1
6 · The paper itself

Abstract

We report the integration of an automated chemical optical sensing unit for the parallel interrogation of 12 BICELLs in a sensing chip. The work was accomplished under the European Project Enviguard (FP7-OCEAN-2013-614057) with the aim of demonstrating an optical nano-biosensing unit for the in-situ detection of various chemical pollutants simultaneously in oceanic waters. In this context, we designed an optical sensing chip based on resonant nanopillars (R-NPs) transducers organized in a layout of twelve biophotonic sensing cells (BICELLs). The sensing chip is interrogated in reflection with a 12-channels optical spectrometer equipped with an embedded computer-on-chip performing image processing for the simultaneous acquisition and analysis (resonant mode fitting) of the 12 spectra. A microfluidic chip and an automated flow control system composed of four pumps and a multi-path micro-valve makes it possible to drive different complex protocols. A rack was designed ad-hoc for the integration of all the modules. As a proof of concept, fluids of different refractive index (RI) were flowed in the system in order to measure the time response (sensogram) of the R-NPs under optical reflectance, and assess the sensors' bulk sensitivity (285.9 ± 16.4 nm/RIU) and Limit of Detection (LoD) (2.95 × 10

Indexed as

automatic systemmicrofluidicsoptical sensorparallel detectionresonant nanopillarssensing

Identifiers

PMID30791592
PMCPMC6412770

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.