Evidence map›Paper›PMID 30791564›Full record

ArticleInternational journal of molecular sciences2019

Differences of the Structure of Immune Regulatory Cell Populations between Cellular Material from Sonographically Detected Focal Thyroid Lesions and Peripheral Blood in Humans.

Mariusz Stasiołek, Przemysław W Śliwka, Magdalena Stasiak, Kinga Krawczyk-Rusiecka, Elżbieta Skowrońska-Jóźwiak, Zbigniew Adamczewski, Andrzej Lewiński

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Toll-Like Receptors-2 and -4 in Graves' Disease-Key Players or Bystanders?International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mariusz StasiołekDepartment of Neurology, Medical University of Lodz, 90-153 Lodz, Poland. mariusz.stasiolek@umed.lodz.pl.
Przemysław W ŚliwkaDepartment of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland. p.sliwka87@gmail.com.
Magdalena StasiakDepartment of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland. mstasiak33@gmail.com.
Kinga Krawczyk-RusieckaDepartment of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland. kinga.krawczyk-rusiecka@umed.lodz.pl.
Elżbieta Skowrońska-JóźwiakDepartment of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland. elzbieta.skowronska-jozwiak@umed.lodz.pl.
Zbigniew AdamczewskiDepartment of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland. zbadam@o2.pl.ORCID 0000-0001-8713-6936
Andrzej LewińskiDepartment of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland. alewin@csk.umed.lodz.pl.ORCID 0000-0002-8748-3337
Medical University of Lodz · PLPolish Mother’s Memorial Hospital Research Institute · PL

Funding

Narodowe Centrum Nauki 2014/15/N/NZ5/03666Polish Mother's Memorial Hospital - Research Institute 2015/IV/43-MN
6 · The paper itself

Abstract

Focal thyroid lesions are common ultrasound findings with the estimated prevalence up to 67% of the population. They form characteristically enveloped regions with individual encapsulated microenvironment that may involve the specific distribution of immune system compounds-especially antigen presenting cells (APC). We analyzed and compared the most potent APC-plasmacytoid and conventional dendritic cells (DCs) subpopulations and three monocyte subpopulations as well as other immune cells-in peripheral blood and local blood of thyroid gland obtained parallelly in patients with focal thyroid lesions using flow cytometry. The analysis revealed significant differences in the distribution of main subsets of assessed cells between peripheral blood and biopsy material. The results support the existence of local, organ-specific immune reaction control networks within thyroid nodules.

Indexed as

Autoimmune DiseasesAutoimmunityBiomarkersDendritic CellsHumansImmune SystemImmunophenotypingKiller Cells, NaturalMonocytesSound SpectrographyThyroid DiseasesBiomarkersautoimmune thyroid diseasedendritic cellsmonocytesthyroidthyroid focal lesion

Identifiers

PMID30791564
PMCPMC6412456
OpenAlexW2916642490

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.