Evidence map›Paper›PMID 30791436›Full record

ArticleMolecules (Basel, Switzerland)2019

Effect of Selected Stilbenoids on Human Fecal Microbiota.

Jose D Jaimes, Veronika Jarosova, Ondrej Vesely, Chahrazed Mekadim, Jakub Mrazek, Petr Marsik, Jiri Killer, Karel Smejkal, Pavel Kloucek, Jaroslav Havlik

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Metabolism of Stilbenoids by Human Faecal Microbiota.Molecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jose D JaimesDepartment of Food Quality and Safety, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague 6-Suchdol, Czech Republic. jose.d.jaimes@gmail.com.ORCID 0000-0002-1598-1855
Veronika JarosovaDepartment of Food Quality and Safety, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague 6-Suchdol, Czech Republic. jarosovaverca@gmail.com.
Ondrej VeselyDepartment of Food Quality and Safety, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague 6-Suchdol, Czech Republic. czeveselyo@gmail.com.
Chahrazed MekadimDepartment of Microbiology, Nutrition and Dietetics, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague 6-Suchdol, Czech Republic. Chahrazedbiotek@gmail.com.ORCID 0000-0002-5793-3501
Jakub MrazekInstitute of Animal Physiology and Genetics, CAS, v.v.i., Videnska 1083, 14220 Prague, Czech Republic. kubino77@gmail.com.ORCID 0000-0003-1907-3333
Petr MarsikDepartment of Food Quality and Safety, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague 6-Suchdol, Czech Republic. marsik@af.czu.cz.
Jiri KillerInstitute of Animal Physiology and Genetics, CAS, v.v.i., Videnska 1083, 14220 Prague, Czech Republic. killer.jiri@seznam.cz.
Karel SmejkalDepartment of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1946/1, 61242 Brno, Czech Republic. karel.mejkal@post.cz.
Pavel KloucekDepartment of Food Quality and Safety, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague 6-Suchdol, Czech Republic. kloucek@af.czu.cz.
Jaroslav HavlikDepartment of Food Quality and Safety, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague 6-Suchdol, Czech Republic. havlik@af.czu.cz.ORCID 0000-0003-1900-0951
Czech University of Life Sciences Prague · CZCzech Academy of Sciences, Institute of Animal Physiology and Genetics · CZUniversity of Veterinary Sciences Brno · CZ

Funding

Česká Zemědělská Univerzita v Praze CIGA 20172031Grantová Agentura České Republiky 16-07193S
6 · The paper itself

Abstract

Dietary phenolics or polyphenols are mostly metabolized by the human gut microbiota. These metabolites appear to confer the beneficial health effects attributed to phenolics. Microbial composition affects the type of metabolites produced. Reciprocally, phenolics modulate microbial composition. Understanding this relationship could be used to positively impact health by phenolic supplementation and thus create favorable colonic conditions. This study explored the effect of six stilbenoids (batatasin III, oxyresveratrol, piceatannol, pinostilbene, resveratrol, thunalbene) on the gut microbiota composition. Stilbenoids were anaerobically fermented with fecal bacteria from four donors, samples were collected at 0 and 24 h, and effects on the microbiota were assessed by 16S rRNA gene sequencing. Statistical tests identified affected microbes at three taxonomic levels. Observed microbial composition modulation by stilbenoids included a decrease in the Firmicutes to Bacteroidetes ratio, a decrease in the relative abundance of strains from the genus

Indexed as

FecesFermentationGastrointestinal MicrobiomeHumansMetagenomeMetagenomicsMolecular StructurePhylogenyRNA, Ribosomal, 16SStilbenesRNA, Ribosomal, 16SStilbenes16S rRNA gene sequencingBacteroidetesbatatasin IIIClostridiumFaecalibacterium prausnitziifermentationFirmicuteshuman colon modelhuman gut microbiotaLachnospiraceaeoxyresveratrolphenolicspiceatannolpinostilbenepolyphenolsresveratrolstilbenoidsthunalbene

Identifiers

PMID30791436
PMCPMC6412329
OpenAlexW2913702969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.