Evidence map›Paper›PMID 30791397›Full record

ArticleInternational journal of molecular sciences2019

cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following

Qiang Li, Chunfa Liu, Ruichao Yue, Saeed El-Ashram, Jie Wang, Xiaoli He, Deming Zhao, Xiangmei Zhou, Lihua Xu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Activation of host nucleic acid sensors byCritical reviews in microbiology · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Huaier Induces Immunogenic Cell DeathFrontiers in cell and developmental biology · 2022
    Article
  16. Review
  17. Review
  18. The Roles of Inflammasomes in Host Defense againstPathogens (Basel, Switzerland) · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Qiang LiCollege of Agriculture, Ningxia University, Xixia District, Yinchuan 750021, China. liqiang5973@163.com.
Chunfa LiuState Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. 15166486220@163.com.
Ruichao YueState Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. yueruichao88@126.com.
Saeed El-AshramCollege of Life Science and Engineering, Foshan University, 18 Jiangwan street, Foshan 528231, China. saeed_elashram@yahoo.com.ORCID 0000-0003-0389-1980
Jie WangState Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. 18611491892@163.com.
Xiaoli HeCollege of Agriculture, Ningxia University, Xixia District, Yinchuan 750021, China. m18295180259@163.com.
Deming ZhaoState Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. zhaodm@cau.edu.cn.
Xiangmei ZhouState Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. zhouxm@cau.edu.cn.ORCID 0000-0003-1566-5745
Lihua XuCollege of Agriculture, Ningxia University, Xixia District, Yinchuan 750021, China. littlezhe99@163.com.
China Agricultural University · CNNingxia University · CNFoshan University · CN

Funding

National Natural Science Foundation of China No. 31560687, No. 31572487, No.31760722Natural Science Foundation of Ningxia Province No. NZ12104, No. NZ15031
6 · The paper itself

Abstract

Cyclic GMP-AMP synthase (cGAS) is an important cytosolic DNA sensor that plays a crucial role in triggering STING-dependent signal and inducing type I interferons (IFNs). cGAS is important for intracellular bacterial recognition and innate immune responses. However, the regulating effect of the cGAS pathway for bone marrow-derived dendritic cells (BMDCs) during

Indexed as

Mycobacterium bovisAnimalsCattleCell DifferentiationCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDendritic CellsFemaleHost-Pathogen InteractionsInterferon Regulatory Factor-3Interferon Type IMembrane ProteinsMiceNucleotidyltransferasesProtein Serine-Threonine KinasesSignal TransductionSTING ProteincGAS protein, mouseCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseInterferon Regulatory Factor-3Interferon Type IMembrane ProteinsNucleotidyltransferasesProtein Serine-Threonine KinasesSting1 protein, mouseSTING ProteinCD4+ T cellscGAS pathwaydendritic cellsMycobacterium bovistype I interferons

Identifiers

PMID30791397
PMCPMC6412216
OpenAlexW2914258016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.