Evidence map›Paper›PMID 30791384›Full record

ArticlePlants (Basel, Switzerland)2019

A Spotlight on Rad52 in Cyanidiophytina (Rhodophyta): A Relic in Algal Heritage.

Angelo Del Mondo, Manuela Iovinella, Milena Petriccione, Angelina Nunziata, Seth J Davis, Diana Cioppa, Claudia Ciniglia

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Prevalent pH Controls the Capacity ofPlants (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angelo Del MondoDepartment of Biology, University of Naples Federico II, Via Cinthia 21, 80126 Naples, Italy. angelo.delmondo@unina.it.
Manuela IovinellaDepartment of Biology, University of York, York YO105DD, UK. mi676@york.ac.uk.ORCID 0000-0002-1035-9071
Milena PetriccioneCREA, Council for Agricultural Research and Economics, Research Centre for Olive, Citrus and Tree Fruit (OFA), Via Torrino 2, 81100 Caserta, Italy. milena.petriccione@crea.gov.it.
Angelina NunziataCREA, Council for Agricultural Research and Economics, Research Centre for Olive, Citrus and Tree Fruit (OFA), Via Torrino 2, 81100 Caserta, Italy. angelina.nunziata@crea.gov.it.ORCID 0000-0002-9946-7334
Seth J DavisDepartment of Biology, University of York, York YO105DD, UK. seth.davis@york.ac.uk.ORCID 0000-0001-5928-9046
Diana CioppaDepartment of Biology, University of Naples Federico II, Via Cinthia 21, 80126 Naples, Italy. dianacioppa@gmail.com.
Claudia CinigliaDepartment of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania "L. Vanvitelli", 81100 Caserta, Italy. claudia.ciniglia@unicampania.it.ORCID 0000-0001-5819-6921

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The RADiation sensitive52 (RAD52) protein catalyzes the pairing between two homologous DNA sequences' double-strand break repair and meiotic recombination, mediating RAD51 loading onto single-stranded DNA ends, and initiating homologous recombination and catalyzing DNA annealing. This article reports the characterization of RAD52 homologs in the thermo-acidophilic Cyanidiophyceae whose genomes have undergone extensive sequencing. Database mining, phylogenetic inference, prediction of protein structure and evaluation of gene expression were performed in order to determine the functionality of the RAD52 protein in Cyanidiophyceae. Its current function in Cyanidiophytina could be related to stress damage response for thriving in hot and acidic environments as well as to the genetic variability of these algae, in which, conversely to extant Rhodophyta, sexual mating was never observed.

Indexed as

CyanidiophytinaextremophilesGaldieriahomologous recombinationRAD52

Identifiers

PMID30791384
PMCPMC6410040

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.