Evidence map›Paper›PMID 30790533›Full record

ArticleNeuron2019

Learning from the Fly Photoreceptor on How Synapses Integrate Gene Expression to Sustain Retina and Brain Function.

Nicolas G Bazan, William C Gordon

Open access · bronzeAbstract readComment
In one paragraph

Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicolas G BazanNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA 70112, USA. Electronic address: nbazan@lsuhsc.edu.
William C GordonNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA 70112, USA.
Louisiana State University Health Sciences Center New Orleans · US

Funding

RPE Messengers, Transcription &Photoreceptor RenewalR01EY005121 · NEI · LSU HEALTH SCIENCES CENTER · PI Nicolas G. Bazan · 1985 to 2026
$9.1M
Novel combinatory therapy for experimental ischemic strokeR01NS104117 · NINDS · LSU HEALTH SCIENCES CENTER · PI BAZAN, NICOLAS G., BELAYEV, LUDMILA S. · 2018 to 2022
$1.6M
NEI NIH HHS R01 EY005121NINDS NIH HHS R01 NS104117
6 · The paper itself

Abstract

Synapse dysfunction is thought to contribute to neurodegenerative diseases. In this issue of Neuron, Tsai et al. (2019) uncover how membrane phospholipid biosynthesis regulates Drosophila photoreceptor (PR) degeneration and the synaptic vesicle pool through a transcriptional-translational feedback loop from the synaptic terminal to the nucleus.

Indexed as

DrosophilaSynaptic VesiclesAnimalsBrainLipidsRetinaSynapsesLipids

Identifiers

PMID30790533
PMCPMC8922300
OpenAlexW2917755932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.