Evidence map›Paper›PMID 30790269›Full record

ArticleHealth services research2019

Will converting naloxone to over-the-counter status increase pharmacy sales?

Sean M Murphy, Jake R Morgan, Philip J Jeng, Bruce R Schackman

Open access · hybridAbstract read
In one paragraph

Article in Health services research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Price Sensitivity and Information Barriers to the Take-Up of Naloxone.American economic journal. Economic policy · 2024
    Article
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  13. Observational
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  17. Considering the Potential Benefits of Over-the-Counter Naloxone.Integrated pharmacy research & practice · 2021
    Review
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sean M MurphyDepartment of Healthcare Policy & Research, Weill Cornell Medical College, New York, New York.ORCID 0000-0001-9104-0670
Jake R MorganDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston, Massachusetts.ORCID 0000-0002-1559-3983
Philip J JengDepartment of Healthcare Policy & Research, Weill Cornell Medical College, New York, New York.ORCID 0000-0002-8336-5536
Bruce R SchackmanDepartment of Healthcare Policy & Research, Weill Cornell Medical College, New York, New York.ORCID 0000-0002-1132-2932
Cornell University · USBoston University · US

Funding

Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI ZACHARY Franklin MEISEL · 2015 to 2026
$20.7M
NIDA NIH HHS P30 DA040500NIDA NIH HHS P30DA040500
6 · The paper itself

Abstract

objectiveTo estimate the own-price elasticity of demand for naloxone, a prescription medication that can counter the effects of an opioid overdose, and predict the change in pharmacy sales following a conversion to over-the-counter status. DATA SOURCES/STUDY

settingThe primary data source was a nationwide prescription claims dataset for 2010-2017. The data cover 80 percent of US retail pharmacies and account for roughly 90 percent of prescriptions filled. Additional covariates were obtained from various secondary data sources. STUDY

designWe estimated a longitudinal, simultaneous equation model of naloxone supply and demand. Our primary variables of interest were the quantity of naloxone sold, measured as total milligrams sold at pharmacies, and the out-of-pocket price paid per milligram, both measured per ZIP Code and quarter-year. DATA COLLECTION/EXTRACTION

methodsPrimary data came directly from payers and processors of prescription drug claims. PRINCIPAL

findingsWe found that, on average, a 1 percent increase in the out-of-pocket price paid for naloxone would result in a 0.27 percent decrease in pharmacy sales. We predict that the total quantity of naloxone sold in pharmacies would increase 15 percent to 179 percent following conversion to over-the-counter status.

conclusionsNaloxone is own-price inelastic, and conversion to over-the-counter status is likely to lead to a substantial increase in total pharmacy sales.

Indexed as

AdultCommerceFemaleHumansMaleMiddle AgedModels, EconomicNaloxoneNarcotic AntagonistsNonprescription DrugsPharmaciesSocioeconomic FactorsNaloxoneNarcotic AntagonistsNonprescription Drugschange in demandnaloxoneopioid overdoseover-the-counter conversion

Identifiers

PMID30790269
PMCPMC6606536
OpenAlexW2915718732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.