Trial reportObesity surgery2019
Efficacy of Intraperitoneal Instillation of Bupivacaine after Bariatric Surgery: Randomized Controlled Trial.
Trial report in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Single-Shot Regional Anesthesia for Bariatric Surgery: a Systematic Review and Network Meta-Analysis.Obesity surgery · 2023Pooled it
- Effect of Intraperitoneal Local Anesthetics in Laparoscopic Bariatric Surgery: A Meta-Analysis of Randomized Controlled Trials.World journal of surgery · 2022Pooled it
- Transversus Abdominis Plane Block Versus Intraperitoneal Local Anesthetics in Bariatric Surgery: A Systematic Review and Network Meta-analysis.Obesity surgery · 2021Pooled it
- Comparison of Preoperative and Postoperative Intraperitoneal Nebulised Ropivacaine in Laparoscopic Gastric Bypass: A Randomised Clinical Trial.Obesity surgery · 2026Trial
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- Trial
- Intraperitoneal Instillation of Local Anesthetic (IPILA) in Bariatric Surgery and the Effect on Post-operative Pain Scores: a Randomized Control Trial.Obesity surgery · 2022Trial
- Analgesic efficacy of intraperitoneal local anaesthetic instillation (IPLA) in laparoscopic bariatric surgery: a systematic review and meta-analysis.Journal of anesthesia, analgesia and critical care · 2026Review
- Effect of intraperitoneal bupivacaine vs magnesium sulfate on early postoperative outcomes after laparoscopic sleeve gastrectomy: a randomized clinical trial.Perioperative medicine (London, England) · 2025Article
- Evidence-Based Perioperative Prevention of Postoperative Nausea and Vomiting (PONV) in Patients Undergoing Laparoscopic Bariatric Surgery: A Scoping Review.Journal of clinical medicine · 2025Review
- Opioid-Free Anesthesia in Bariatric Surgery: Is It the One and Only? A Comprehensive Review of the Current Literature.Healthcare (Basel, Switzerland) · 2024Review
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- Propensity score matched analysis of postoperative nausea and pain after one anastomosis gastric bypass (MGB/OAGB) versus sleeve gastrectomy (SG).Updates in surgery · 2023Article
- Solve study: a study to capture global variations in practices concerning laparoscopic cholecystectomy.Surgical endoscopy · 2022Article
- Enhanced recovery after bariatric surgery: an Italian consensus statement.Surgical endoscopy · 2022Article
- Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations: A 2021 Update.World journal of surgery · 2022Review
- Efficacy of intraperitoneal bupivacaine in laparoscopic bariatric surgery.Annals of medicine and surgery (2012) · 2022Article
- Patients with sleep-disordered breathing for bariatric surgery.Saudi journal of anaesthesiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionObesity is one of the greatest health problems. Bariatric surgery is more effective than non-surgical options; however, postoperative pain is bound to a greater morbidity. Control of postoperative pain is important in facilitating patient convalescence. In this study, we assessed the efficacy of intraperitoneal instillation of bupivacaine after bariatric surgery.
methodsA hundred patients who underwent bariatric procedures including sleeve gastrectomy, sleeve gastrectomy with cardioplasty, gastric bypass, and gastric mini bypass (one anastomosis gastric bypass) were included in the study. Patients were divided into two groups randomly, 50 patients for each; group I had intraperitoneal instillation of 40 ml bupivacaine 0.25% at the end of the procedure, while group II had normal saline instillation. Monitoring of pain control in the first 24 h after surgery was done using the visual analogue scale (VAS) to assess the efficacy of intraperitoneal bupivacaine instillation and its effect on the overall opioid usage, postoperative nausea and vomiting (PONV), and shoulder tip pain.
resultsPain scores were significantly lower in group I compared to group II at recovery, 2, 4 and 6 h after surgery, P = 0.004, 0.001, < 0.001, and 0.001 respectively. However, there were no significant differences between 12 and 24 h postoperatively. Additionally, there was a significant difference regarding the need for rescue analgesia at recovery P = < 0.001
conclusionsIntraperitoneal instillation of bupivacaine provides a good analgesia in the early postoperative period, reduces the overall consumption of opioid, and decreases the rescue analgesia requirement in the first 24 h after surgery.
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Identifiers
30790163What OpenQuestion holds
Registered trials
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