Evidence map›Paper›PMID 30790130›Full record

ArticleJournal of natural medicines2019

Two new quassinoids and other constituents from Picrasma javanica wood, and their biological activities.

Prema, Chin Piow Wong, Alfarius Eko Nugroho, Maurice Ducret Awouafack, Yi Yi Win, Nwet Nwet Win, Hla Ngwe, Hiroshi Morita, Hiroyuki Morita

Abstract read
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In one paragraph

Article in Journal of natural medicines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Triterpenoids from Walsura trichostemon.Journal of natural medicines · 2021
    Article
  7. Bisindole alkaloids from Voacanga grandifolia leaves.Journal of natural medicines · 2021
    Article
  8. Bioactive Compounds from Medicinal Plants in Myanmar.Progress in the chemistry of organic natural products · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

PremaInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Chin Piow WongInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Alfarius Eko NugrohoFaculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan.
Maurice Ducret AwouafackInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Yi Yi WinDepartment of Chemistry, University of Yangon, Yangon, 11041, Myanmar.
Nwet Nwet WinInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Hla NgweDepartment of Chemistry, University of Yangon, Yangon, 11041, Myanmar.
Hiroshi MoritaFaculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan. moritah@hoshi.ac.jp.
Hiroyuki MoritaInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan. hmorita@inm.u-toyama.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Picrasma javanica Blume (Simaroubaceae) is a medium-sized tree that is distributed widely in tropical Asia. In our previous study, we isolated quassinoids from P. javanica bark collected in Myanmar, and reported their antiproliferative activities. In our ongoing research for the discovery of bioactive compounds from Myanmar medicinal plants, two new quassinoids, (16R)-methoxyjavanicin B (1) and (16S)-methoxyjavanicin B (2), along with seven known compounds (3-9), were isolated during the phytochemical investigation of the CHCl

Indexed as

A549 CellsAnti-Bacterial AgentsBacillus subtilisCell Line, TumorCell ProliferationHeLa CellsHumansMCF-7 CellsMicrobial Sensitivity TestsMolecular StructureMyanmarNeoplasmsPicrasmaPlant ExtractsPlants, MedicinalQuassinsAnti-Bacterial AgentsPlant ExtractsQuassins(16R)-Methoxyjavanicin B(16S)-Methoxyjavanicin BAntibacterialCytotoxicityPicrasma javanicaQuassinoids

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.