Evidence map›Paper›PMID 30790043›Full record

ArticleInternational archives of occupational and environmental health2019

Neurobehavioral performance of patients diagnosed with manganism and idiopathic Parkinson disease.

Dag G Ellingsen, Grigoriy Shvartsman, Rita Bast-Pettersen, Maxim Chashchin, Yngvar Thomassen, Valery Chashchin

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International archives of occupational and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Dag G EllingsenNational Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway. dag.ellingsen@stami.no.ORCID http://orcid.org/0000-0002-7607-6701
Grigoriy ShvartsmanNorthwest State Medical University named after I.I. Mechnikov, 191015, St. Petersburg, Russia.
Rita Bast-PettersenNational Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway.
Maxim ChashchinNorthwest Public Health Research Centre, St. Petersburg, 191036, Russia.
Yngvar ThomassenNational Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway.
Valery ChashchinNorthwest State Medical University named after I.I. Mechnikov, 191015, St. Petersburg, Russia.
National Institute of Occupational Health · NONorth-Western State Medical University named after I.I. Mechnikov · RUCity Clinical Oncology Center · RU

Funding

U.S. Army W81XWH-05-1-0239
6 · The paper itself

Abstract

purposeThere is a lack of knowledge about neurobehavioral performance among patients with manganism and how their performance differs from that of idiopathic Parkinson disease patients (PD). This study was initiated with the aim to describe and compare neurobehavioral performance among patients diagnosed with manganism, PD and a group of referents. MATERIALS AND

methodsNeurobehavioral performance was assessed in 34 patients diagnosed with manganism, 13 with PD, and 43 healthy workers (turners/fitters) who served as the reference group. Seventeen of the manganism patients had also been tested approximately 65 months previously.

resultsManganism patients scored substantially more poorly than referents on tests for motor speed, manual dexterity and balance. They also performed more poorly than the PD patients on the postural sway test. In contrast, the PD patients had higher postural tremor intensity with narrower frequency dispersion than manganism patients. The pattern of neurobehavioral performance was more asymmetrical in PD compared to manganism patients, in particular when testing for tremor intestity, grooved pegboard and static steadiness, indicating lateralized impairment in the PD patients. The amount of bradykinesia was comparable between the patient groups. Neurobehavioral performance deteriorated slightly among 17 manganism patients followed for 65 months compared with the age-related decline among referents.

conclusionsPatients with manganism had severe bradykinesia and balance disturbances, but only slight postural tremor. In contrast, PD patients had significant postural tremor and bradykinesia, but only slight balance disturbances. Their neurobehavioral performance indicated lateralized impairment, more unilateral. Neurobehavioral performance deteriorated slightly in manganism patients during a 65-month follow-up.

Indexed as

Psychomotor PerformanceAgedAged, 80 and overFemaleFollow-Up StudiesFunctional LateralityHumansHypokinesiaMaleManganese PoisoningMiddle AgedMotor SkillsNervous System DiseasesNeuropsychological TestsOccupational ExposureParkinson DiseaseManganeseNeurobehavioral performanceWelders

Identifiers

PMID30790043
OpenAlexW2917024761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.