SynthesisInternational journal of public health2019
Health effects of ultrafine particles: a systematic literature review update of epidemiological evidence.
Synthesis in International journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
107 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Systematic review and meta-analysis on the health effects of long-term exposure to ultrafine particles.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- The long-term effect of exposure to respirable particulate matter on the incidence of myocardial infarction: a systematic review and meta-analysis study.Environmental science and pollution research international · 2022Pooled it
- Years of Life Lost (YLL) Due to Short-Term Exposure to Ambient Air Pollution in China: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Meta-analysis on short-term exposure to ambient ultrafine particles and respiratory morbidity.European respiratory review : an official journal of the European Respiratory Society · 2020Pooled it
- Effect of HEPA Filtration Air Purifiers on Blood Pressure: A Pragmatic Randomized Crossover Trial.Journal of the American College of Cardiology · 2025Trial
- Effect of Reducing Ambient Traffic-Related Air Pollution on Blood Pressure: A Randomized Crossover Trial.Hypertension (Dallas, Tex. : 1979) · 2021Trial
- Acute Blood Pressure and Cardiovascular Effects of Near-Roadway Exposures With and Without N95 Respirators.American journal of hypertension · 2019Trial
- Advancing Long-Term Outdoor Air Pollution Exposure Assessment for Health Studies: Lessons from a Multinational Research Initiative.Current environmental health reports · 2026Review
- Air quality and health implications of exposure to ultrafine particle pollution.Cardiovascular research · 2026Article
- Ultrafine Particles and Mortality: A Scoping Review of Epidemiologic Evidence and Exposure Assessment Limitations.Toxics · 2026Review
- Nanoparticle-Encapsulated 5-Azacytidine Attenuates Air Pollution-Induced Human Cardiac Fibroblast Activation.Cardiovascular toxicology · 2026Article
- Improving Inference in Air Pollution Epidemiology: The Case for Rethinking Multipollutant Adjustment.Epidemiology (Cambridge, Mass.) · 2026Article
- Changes of Long-Term Exposure to Ultrafine Particles From 2010 to 2019 in High Income Countries in Relation to Cardiovascular Diseases.GeoHealth · 2026Article
- Review
- Clinical Implications of Post-Earthquake Environmental Exposures in Children with Allergic Diseases.Journal of clinical medicine · 2026Article
- Mortality risks associated with short-term exposure to ultrafine particles in London and the West Midlands.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- PAH-associated health risk from ultrafine particles: an urban field study.Air quality, atmosphere, & health · 2026Article
- Estimating the environmental burden of disease in children and adolescents in Germany: limitations and possible solutions.Frontiers in public health · 2026Article
- Global high-resolution ultrafine particle number concentrations through data fusion with machine learning.Scientific data · 2025Article
- Short-term exposure to ultrafine particles and asthma hospital admissions in children in Copenhagen, Denmark.Thorax · 2025Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesDue to their small size, ultrafine particles (UFP) are believed to exert higher toxicity than larger particles. As numerous studies on health effects of UFP have been published since the last systematic review in 2013, we aim to systematically review the new literature.
methodsWe searched MEDLINE and the specialized LUDOK database for studies published between 01.01.2011 and 11.05.2017 investigating health effects of ambient air pollution-related UFP. We included epidemiologic studies containing UFP measures and quantifiable measures of associations. Relevant data were extracted on the basis of previously developed evaluation criteria.
resultsWe identified 85 original studies, conducting short-term (n = 75) and long-term (n = 10) investigations. Panel (n = 32), scripted exposure with predefined settings (n = 16) or time series studies (n = 11) were most frequent. Thirty-four studies adjusted for at least one other pollutant. Most consistent associations were identified for short-term effects on pulmonary/systemic inflammation, heart rate variability and blood pressure.
conclusionsThe evidence suggests adverse short-term associations with inflammatory and cardiovascular changes, which may be at least partly independent of other pollutants. For the other studied health outcomes, the evidence on independent health effects of UFP remains inconclusive or insufficient.
Indexed as
Identifiers
30790006What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.