Evidence map›Paper›PMID 30789999›Full record

Observational studyOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2019

Visit-to-visit blood pressure variability and hip fracture risk in older persons.

T-C Li, C-I Li, C-S Liu, W-Y Lin, C-H Lin, S-Y Yang, J-H Chiang, C-C Lin

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Lifetime risks of hip fracture in patients with type 2 diabetic: Taiwan Diabetes Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

T-C LiDepartment of Public Health, College of Public Health, China Medical University, Taichung, Taiwan.
C-I LiDepartment of Medical Research, China Medical University Hospital, Taichung, Taiwan.
C-S LiuDepartment of Medical Research, China Medical University Hospital, Taichung, Taiwan.
W-Y LinSchool of Medicine, College of Medicine, China Medical University, 91 Hsueh-Shih Road, Taichung, 40421, Taiwan.
C-H LinSchool of Medicine, College of Medicine, China Medical University, 91 Hsueh-Shih Road, Taichung, 40421, Taiwan.
S-Y YangDepartment of Public Health, College of Public Health, China Medical University, Taichung, Taiwan.
J-H ChiangManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
C-C LinDepartment of Medical Research, China Medical University Hospital, Taichung, Taiwan. cclin@mail.cmuh.org.tw.ORCID http://orcid.org/0000-0002-9625-6216
China Medical University · TWAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the association between blood pressure variability measured by the coefficient of variation (CV) of blood pressure and hip fracture in older persons with diabetes. After excluding patients with acute complications and comorbidities, a positive association with similar magnitude of strength was found between BP variability and hip fracture, compared with that in the original analysis.

introductionHypertension is a risk factor of osteoporosis and hip fracture, but studies have yet to investigate whether blood pressure variability measured by the CV of blood pressure can predict hip fracture in older persons with diabetes.

methodsWe conducted a retrospective cohort study on 21,160 patients who suffered from type 2 diabetes (age ≥ 50 years) and participated in the National Diabetes Care Management Program in Taiwan. The patients' 1-year variability in systolic blood pressure (SBP) and diastolic blood pressure (DBP) at the baseline and subsequent hip fracture incidence for 8.2 years were analyzed.

resultsThere were 937 recorded incident hip fractures. SBP-CV and DBP-CV were classified based on their tertiles. After multivariate adjustment was conducted, SBP-CV found to be a predictor of hip fracture, and its hazard ratio was 1.18 (95% CI 1.00-1.40) for the third tertile compared with the first tertile.

conclusionsOur study suggests SBP stability is a predictor for hip fracture incidence in older persons with type 2 diabetes.

Indexed as

AgedBlood PressureDiabetes Mellitus, Type 2FemaleHip FracturesHumansHypertensionMaleMiddle AgedOsteoporotic FracturesRetrospective StudiesRisk AssessmentRisk FactorsTaiwanBlood pressureDiabetesHip fracture

Identifiers

PMID30789999
OpenAlexW2915439078

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.