ArticlePLoS pathogens2019
Plant begomoviruses subvert ubiquitination to suppress plant defenses against insect vectors.
Article in PLoS pathogens, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 103 citations in OpenAlex.
- The Ubiquitin-Proteasome System Plays Dual Roles in Plant Antiviral Defense and Viral Pathogenicity.Plants (Basel, Switzerland) · 2026Review
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- The zig-zag model of molecular defense and counterdefense in plant-herbivore interactions.Planta · 2026Review
- Differential Performance of Vector and Non-Vector Planthoppers on Virus-Infected vs. Mock-Infected Plants.Insects · 2026Article
- A Bacterial Effector Hijacks NBR1 to Modulate Both Autophagy and Ubiquitination-Mediated Degradation That Promotes Bacterial Infection.Plant biotechnology journal · 2026Article
- Genomic insight of plant pathogen, begomovirus and vector cross-talk: an emerging strategy to tackle the leaf curl disease.Molecular biology reports · 2026Review
- The βC1 protein encoded in betasatellites promotes begomovirus-whitefly coexistence by subverting vector infestation-induced plant antiviral defenses.PLoS pathogens · 2026Article
- First genomic insights into the introgression of almond PPV-Marcus resistance into peach.Frontiers in plant science · 2026Article
- Virus-Inducible Activation of Hypersensitive Response Confers Broad-Spectrum Resistance to Diverse Viruses in Plants.Molecular plant pathology · 2025Article
- A fijivirus capsid protein hijacks autophagy degrading an ω-3 fatty acid desaturase to suppress jasmonate-mediated antiviral defence.Plant biotechnology journal · 2025Article
- Neophytadiene, a Plant Specialized Metabolite, Mediates the Virus-Vector-Plant Tripartite Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Turnip mosaic virus infection cleaves MEDIATOR SUBUNIT16 in plants increasing plant susceptibility to the virus and its aphid vector Myzus persicae.BMC plant biology · 2025Article
- The Turnip Yellows Virus Capsid Protein Promotes Access of Its Main Aphid Vector Myzus persicae to Phloem Tissues.Plant, cell & environment · 2025Article
- A viral movement protein mediates host volatile biosynthesis to co-attract vectors and non-vectors and enhances viral infection.Frontiers in plant science · 2025Article
- Protein Dynamics in Plant Immunity: Insights into Plant-Pest Interactions.International journal of molecular sciences · 2024Review
- Transcriptional Modulation of Plant Defense Genes by a Bipartite Begomovirus Promotes the Performance of Its Whitefly Vector.Viruses · 2024Article
- A plant virus differentially alters DNA methylation in two cryptic species of a hemipteran vector.Npj viruses · 2024Article
- Article
- Two genes encoded by mulberry crinkle leaf virus (MCLV): The V4 gene enhances viral replication, and the V5 gene is needed for MCLV infection in Nicotiana benthamiana.Virus research · 2024Article
- Rice stripe virus nonstructural protein 3 suppresses plant defence responses mediated by the MEL-SHMT1 module.Molecular plant pathology · 2023Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most plant viruses are vectored by insects and the interactions of virus-plant-vector have important ecological and evolutionary implications. Insect vectors often perform better on virus-infected plants. This indirect mutualism between plant viruses and insect vectors promotes the spread of virus and has significant agronomical effects. However, few studies have investigated how plant viruses manipulate plant defenses and promote vector performance. Begomoviruses are a prominent group of plant viruses in tropical and sub-tropical agro-ecosystems and are transmitted by whiteflies. Working with the whitefly Bemisia tabaci, begomoviruses and tobacco, we revealed that C2 protein of begomoviruses lacking DNA satellites was responsible for the suppression of plant defenses against whitefly vectors. We found that infection of plants by tomato yellow leaf curl virus (TYLCV), one of the most devastating begomoviruses worldwide, promoted the survival and reproduction of whitefly vectors. TYLCV C2 protein suppressed plant defenses by interacting with plant ubiquitin. This interaction compromised the degradation of JAZ1 protein, thus inhibiting jasmonic acid defense and the expression of MYC2-regulated terpene synthase genes. We further demonstrated that function of C2 protein among begomoviruses not associated with satellites is well conserved and ubiquitination is an evolutionarily conserved target of begomoviruses for the suppression of plant resistance to whitefly vectors. Taken together, these results demonstrate that ubiquitination inhibition by begomovirus C2 protein might be a general mechanism in begomovirus, whitefly and plant interactions.
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