Evidence map›Paper›PMID 30789940›Full record

SynthesisPloS one2019

Is there an association between diabetes and neck and back pain? A systematic review with meta-analyses.

Daniel Pozzobon, Paulo H Ferreira, Amabile B Dario, Lisandra Almeida, Giovana Vesentini, Alison R Harmer, Manuela L Ferreira

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Healthcare resource utilization for chronic low back pain among high-utilizers.The spine journal : official journal of the North American Spine Society · 2024
    Article
  6. Causations between obesity, diabetes, lifestyle factors and the risk of low back pain.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  7. The relationship between chronic diseases and the intensity and duration of low back pain.European journal of physical and rehabilitation medicine · 2024
    Observational
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Daniel PozzobonInstitute of Bone and Joint Research, The Kolling Institute, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-2796-4235
Paulo H FerreiraMusculoskeletal Health Research Group, Faculty of Health Sciences, University of Sydney, Sydney, NSW, Australia.
Amabile B DarioSchool of Public Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Lisandra AlmeidaDiscipline of Physiotherapy, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Giovana VesentiniDepartment of Gynaecology and Obstetrics, Botucatu Medical School, UNESP-Paulista State University, Botucatu, São Paulo, Brazil.ORCID 0000-0002-7116-1667
Alison R HarmerMusculoskeletal Health Research Group, Faculty of Health Sciences, University of Sydney, Sydney, NSW, Australia.
Manuela L FerreiraInstitute of Bone and Joint Research, The Kolling Institute, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
The University of Sydney · AUUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveApproximately half of the population will experience either low back pain or neck pain, at some point in their lives. Previous studies suggest that people with diabetes are more likely to present with chronic somatic pain, including shoulder, knee and spinal pain. This study aimed to systematically review and appraise the literature to explore the magnitude as well as the nature of the association between diabetes and back, neck, or spinal (back and neck) pain. DATABASES AND DATA TREATMENT: A systematic search was performed using the Medline, CINAHL, EMBASE, and Web of Science electronic databases. Studies which assessed the association between diabetes and back or neck pain outcomes, in participants older than 18 years of age were included. Two independent reviewers extracted data on the incidence of pain and reported associations.

resultsEight studies were included in the meta-analyses. Meta-analyses showed that people with diabetes are more likely to report low back pain [5 studies; n: 131,431; odds ratio (OR): 1.35; 95% Confidence Interval (CI): 1.20 to 1.52; p<0.001] and neck pain (2 studies; n: 6,560; OR: 1.24; 95% CI: 1.05 to 1.47; p = 0.01) compared to those without diabetes. Results from one longitudinal cohort study suggested that diabetes is not associated with the risk of developing future neck, low back or spinal pain.

conclusionsDiabetes is associated with low back and neck individually, and spinal pain. The longitudinal analysis showed no association between the conditions. Our results suggest that diabetes co-exists with back pain; however, a direct causal link between diabetes and back pain was not established. SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration CRD42016050738.

Indexed as

CanadaDiabetes MellitusEuropeHumansLongitudinal StudiesLow Back PainNeck PainObservational Studies as TopicUnited States

Identifiers

PMID30789940
PMCPMC6383876
OpenAlexW2916181402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.