Evidence map›Paper›PMID 30789906›Full record

ArticlePLoS neglected tropical diseases2019

Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming.

David J Williams, Mohd Abul Faiz, Bernadette Abela-Ridder, Stuart Ainsworth, Tommaso C Bulfone, Andrea D Nickerson, Abdulrazaq G Habib, Thomas Junghanss, Hui Wen Fan, Michael Turner and 2 more

2 registry-linked trialsAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 215 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
215citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04210141 phase2suspendednot on this mapstarted 2025, after this paper: background citation

An Adaptive Clinical Trial to Determine the Optimal Initial Dose of Lyophilized, Species Specific Monovalent Antivenom for the Management of Systemic Envenoming by Daboia Siamensis (Eastern Russell's Viper) in Myanmar

TypeinterventionalSponsorMyanmar Oxford Clinical Research UnitRan2025 to 2027Enrolled200ConditionsDaboia Siamensis EnvenomingArmslyophilized BPI viper antivenom
NCT04996264 phase2completednot on this mapstarted 2021, after this paper: background citation

Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of a Multi-Dose Regimen of Oral Varespladib-Methyl in Subjects Bitten by Venomous Snakes

TypeinterventionalSponsorOphirex, Inc.Ran2021 to 2023Enrolled95ConditionsSnakebites, Envenoming, Envenoming, Snake, Envenomation, SnakeArmsVarespladib Methyl, Placebo, Standard of care (SOC)
3 · Its place in the literature

Who cites it

215 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A systematic review of variables associated with snakebite risk in spatial and temporal analyses.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025
    Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Toxicon: X · 2026
    Article
  20. Article

155 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David J WilliamsAustralian Venom Research Unit, Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0002-6838-4632
Mohd Abul FaizChittagong Medical College Hospital, Chittagong, Bangladesh.
Bernadette Abela-RidderDepartment for the Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
Stuart AinsworthAlistair Reid Venom Research Unit, Parasitology Department, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom.ORCID 0000-0002-0199-6482
Tommaso C BulfoneCalifornia Academy of Sciences, San Francisco, California, United States of America.ORCID 0000-0002-3458-920X
Andrea D NickersonCalifornia Academy of Sciences, San Francisco, California, United States of America.
Abdulrazaq G HabibDepartment of Medicine, College of Health Sciences, Bayero University Kano, Kano, Nigeria.
Thomas JunghanssSection Clinical Tropical Medicine, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0002-9229-0193
Hui Wen FanDivisão Bioindustrial, Instituto Butantan, São Paulo, Brazil.
Michael TurnerInfection and Immuno-Biology, Wellcome, London, United Kingdom.
Robert A HarrisonChittagong Medical College Hospital, Chittagong, Bangladesh.ORCID 0000-0001-9842-5573
David A WarrellNuffield Department of Clinical Medicine, University of Oxford, United Kingdom.ORCID 0000-0001-7792-1615

Funding

Medical Research Council MC_PC_15040Medical Research Council MC_PC_17167Medical Research Council MR/L01839X/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/K500288/1Wellcome TrustWorld Health Organization 001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neglected DiseasesTropical MedicineAnimalsAntiveninsHealth PromotionHealth Services AccessibilityHumansIncidenceSnake BitesSocioeconomic FactorsAntivenins

Identifiers

PMID30789906
PMCPMC6383867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.