ReviewCurrent opinion in rheumatology2019
Depression and the risk of rheumatoid arthritis.
Review in Current opinion in rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 131 citations in OpenAlex.
- The Depression Prevalence in Chinese Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis.Actas espanolas de psiquiatria · 2023Pooled it
- Assessment of bidirectional relationships between depression and rheumatoid arthritis among adults: a two-sample Mendelian randomization study.Clinical rheumatology · 2023Pooled it
- Health status and self-management in patients with inflammatory arthritis-A five-year follow-up study after nurse-led patient education.Nursing open · 2020Trial
- Global population-level concurrence and directional associations between rheumatoid arthritis and depressive disorders: an SDI-stratified time-series analysis using GBD 2021.Clinical rheumatology · 2026Article
- Psychological Stress and Anxiety in Autoimmune Diseases: A Cross-Sectional Case-Control Study.Healthcare (Basel, Switzerland) · 2026Article
- Arthritis and longitudinal trajectories of depressive symptoms and cognition in middle-aged and older adults: a prospective tri-cohort study.Archives of public health = Archives belges de sante publique · 2026Article
- Towards an individualised approach to pain management in inflammatory arthritis.Therapeutic advances in musculoskeletal disease · 2026Review
- Brain-bone axis dysregulation: Biological code underlying the bidirectional association between depression and musculoskeletal disorders.Journal of orthopaedic translation · 2026Review
- Quality of Life in Long-Standing Rheumatoid Arthritis: What Can Help Apart from Treatment? A Single-Center Cross-Sectional Observational Study.Journal of clinical medicine · 2025Article
- The relation between clinical characteristics and mental health in patients with rheumatoid arthritis.Scientific reports · 2025Article
- Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population-Based Study Using Administrative Data.Arthritis care & research · 2025Article
- Mentalizing, Loneliness and Pain-Related Depressive Symptoms Are Associated with Pain Severity in Patients with Rheumatic Diseases: Results of a Cross-Sectional Secondary Analysis.Journal of clinical medicine · 2025Article
- Burden of Emergency Department Visits and Their Outcomes Among Patients With Rheumatoid Arthritis: Insights From the Nationwide Emergency Department Sample.ACR open rheumatology · 2025Article
- The Combined Treatment of Chinese Herbal Medicines Is Correlated with a Lower Risk of Rheumatoid Arthritis in Patients with Depression: Evidence from a Population-Based Patient-Control Study.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Trajectories of health status and their association with rheumatoid arthritis risk: insights from a national prospective cohort study.BMC public health · 2025Article
- Identifying behavior regulatory leverage over mental disorders transcriptomic network hubs toward lifestyle-dependent psychiatric drugs repurposing.Human genomics · 2025Article
- Health-related quality of life and disease activity in rheumatoid arthritis: a cross-sectional study in West Java, Indonesia.Frontiers in medicine · 2025Article
- Abnormalities of lipid metabolism in the progression and treatment of depression.Frontiers in psychiatry · 2025Review
- Application of Elastic networks and Bayesian networks to explore influencing factors associated with arthritis in middle-aged and older adults in the Chinese community.Frontiers in public health · 2025Article
- Association of improvement and worsening of depressive symptoms with arthritis.BMC geriatrics · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewRheumatoid arthritis (RA) is associated with negative changes in mental health. This is generally attributed to symptoms of inflammation and the adverse impact of RA on quality of life and functioning. Until recently, causal pathways in the opposite direction have not been fully appreciated. This review examines the recent literature on the risk of RA associated with depression. RECENT
findingsCurrent literature links depression with an increased risk of RA and with a more detrimental disease course. These effects are likely to be partially mediated by negative effects of depression on coping with RA and on factors such as medication adherence, both of which lead to poorer disease outcomes. Growing evidence also suggests that inflammation is central both to depression and RA and may account for some of the complex interplay between these conditions. SUMMARY: Awareness of a bidirectional relationship between depression and RA through a biopsychosocial framework may assist clinicians in maintaining an appropriate index of suspicion about the co-occurrence of these conditions. This review also suggests an important need for integration of rheumatologic and mental health services and generates hypotheses for future research towards a better understanding of both depression and RA.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.