ArticleAmerican journal of respiratory and critical care medicine2019
Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis.
Registry-linked trialOpen access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05674994 (Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis), which is not on this map. Cited by 233 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
233citing papers in PubMed, 3 pooled it
32.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis: a Randomized Controlled Trial
Who cites it
233 citing papers in PubMed, 3 syntheses or guidelines pooled it, 355 citations in OpenAlex.
- The Role of Lung Microbiome in Fibrotic Interstitial Lung Disease-A Systematic Review.Biomolecules · 2024Pooled it
- The Human Respiratory Microbiome: Current Understandings and Future Directions.American journal of respiratory cell and molecular biology · 2023Pooled it
- The Role of Herpes Viruses in Pulmonary Fibrosis.Frontiers in medicine · 2021Pooled it
- Azithromycin Exposure Induces Transient Microbial Composition Shifts and Decreases the Airway Microbiota Resilience from Outdoor PMMicrobiology spectrum · 2023Trial
- Trial
- The role of the respiratory microbiome in acute and chronic respiratory diseases.Nature reviews. Microbiology · 2026Review
- Acute exacerbation in fibrotic interstitial lung disease: an international working group report.American journal of respiratory and critical care medicine · 2026Review
- Gut microbiota associate with disease severity and survival in idiopathic pulmonary fibrosis.American journal of respiratory and critical care medicine · 2026Article
- Comparative study on mouse models of acute exacerbation of pulmonary fibrosis.Experimental and therapeutic medicine · 2026Article
- Unravelling the Links Between Gastroesophageal Reflux and Lung Disease: New Insights.Digestive diseases and sciences · 2026Review
- Dynamic balance of the lung microbiome in health and respiratory diseases.Chinese medical journal · 2026Review
- Article
- The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut-Lung Axis.Phytotherapy research : PTR · 2026Review
- The Gut-Lung Microbiome Axis in Alveolar Stem Cell Regeneration and Lung Repair.Microorganisms · 2026Review
- A Harmonized Respiratory-Gut Microbiome Cohort Framework for Idiopathic Pulmonary Fibrosis.Tuberculosis and respiratory diseases · 2026Article
- Integrated Analysis of the Lung Microbiome and Metabolome Reveals Associations Between Amino Acid Metabolism and Pulmonary Fibrosis in a Bleomycin-Induced Mouse Model.International journal of molecular sciences · 2026Article
- Sputum lautropia is decreased in rheumatoid arthritis-associated pulmonary fibrosis.Arthritis research & therapy · 2026Article
- Hallmarks of the ageing lung: 10 years later.The European respiratory journal · 2026Review
- The clinical and translational perspectives on the lung microbiome in interstitial lung diseases: a bibliometric review.Journal of thoracic disease · 2026Article
- Recent advances in pulmonary fibrosis: from lung surfactant to the immune connection.Respiratory research · 2026Review
173 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
18 authors at 3 institutions in 1 country.
David N O'Dwyer1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.ORCID 0000-0003-3214-380X
Shanna L Ashley1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Stephen J Gurczynski1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Meng Xia2 Department of Biostatistics, School of Public Health, and.
Carol Wilke1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Nicole R Falkowski1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Katy C Norman3 Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
Kelly B Arnold3 Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
Gary B Huffnagle1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Margaret L Salisbury1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.ORCID 0000-0001-8217-6955
MeiLan K Han1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Kevin R Flaherty1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Eric S White1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Fernando J Martinez5 Department of Internal Medicine, Weill Cornell School of Medicine, New York, New York; and.
John R Erb-Downward1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.
Susan Murray2 Department of Biostatistics, School of Public Health, and.
Bethany B Moore1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.ORCID 0000-0003-3051-745X
Robert P Dickson1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.ORCID 0000-0002-6875-4277
Pulmonary and Critical Care Associates · USUniversity of Michigan · USCornell University · US
Funding
Michigan Mouse Metabolic Phenotyping CenterU2CDK110768 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELIAS, CAROL FUZETI · 2016 to 2021
$6.2MImmunobiology of Lung Injury and FibrosisR35HL144481 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2019 to 2024
$5.2MFunctional Analysis of the Pulmonary Microbiome during COPDR01HL121774 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUFFNAGLE, GARY B · 2017 to 2020
$3.1MmiR-29b and autophagy regulate alveolar macrophage function post-BMTR01AI117229 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2015 to 2019
$2.2MThe role of the lung microbiome in oxygen-induced lung injuryR01HL144599 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DICKSON, ROBERT PICKETT · 2019 to 2023
$2.1MHSCT-induced alterations in DCs to promote IL-17 and lung pathologyR01HL127805 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2016 to 2018
$1.5MThe Role of the Microbiome in the Acute Respiratory Distress SyndromeK23HL130641 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DICKSON, ROBERT PICKETT · 2016 to 2020
$859kHost Response, Lung Microbiome, and Clinical Phenotype in Hypersensitivity PneumoniaK23HL141539 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SALISBURY, MARGARET LOUISE · 2019 to 2023
$856kRapid pathogen identification in pneumonia using real-time metagenomics and ultrasensitive PCRR21AI137669 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DICKSON, ROBERT PICKETT · 2018 to 2019
$429kToll-like receptors and respiratory microbiota interactions in idiopathic pulmonary fibrosisK99HL139996 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'DWYER, DAVID NOEL · 2018 to 2019
$265kNHLBI NIH HHS K23 HL130641NHLBI NIH HHS K23 HL141539NHLBI NIH HHS K99 HL139996NHLBI NIH HHS L30 HL138825NHLBI NIH HHS R01 HL121774NHLBI NIH HHS R01 HL127805NHLBI NIH HHS R35 HL144481NIAID NIH HHS R01 AI117229NIAID NIH HHS R21 AI137669NIDDK NIH HHS U2C DK110768
Abstract
PubMed holds no abstract for this paper.
Indexed as
AgedAnimalsBronchoalveolar Lavage FluidDisease Models, AnimalDisease ProgressionFemaleFlow CytometryGerm-Free LifeHumansIdiopathic Pulmonary FibrosisInflammationLungMaleMiceMice, Inbred C57BLMicrobiotaRNA, Ribosomal, 16Sbleomycingerm freeidiopathic pulmonary fibrosisinflammationlung microbiota
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT05674994ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.