Evidence map›Paper›PMID 30789545›Full record

ArticleNursing research

Maternal Adverse Childhood Experiences, Family Strengths, and Chronic Stress in Children.

Eileen M Condon, Margaret L Holland, Arietta Slade, Nancy S Redeker, Linda C Mayes, Lois S Sadler

Open access · greenAbstract read
In one paragraph

Article in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  4. Childhood Adversities and the ATTACHInternational journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eileen M CondonEileen M. Condon, PhD, APRN, FNP-BC, is Postdoctoral Fellow, Yale School of Nursing, Orange, Connecticut. Margaret L. Holland, PhD, MPH, MS, is Associate Research Scientist, Yale School of Nursing, Orange, Connecticut. Arietta Slade, PhD, is Clinical Professor, Yale Child Study Center, New Haven, Connecticut. Nancy S. Redeker, PhD, RN, FAHA, FAAN, is Professor, Yale School of Nursing and Yale School of Medicine, New Haven, Connecticut. Linda C. Mayes, MD, is Professor and Chair, Yale Child Study Center, New Haven, Connecticut. Lois S. Sadler, PhD, RN, FAAN, Professor, Yale School of Nursing and Yale Child Study Center, New Haven, Connecticut.
Margaret L Holland
Arietta Slade
Nancy S Redeker
Linda C Mayes
Lois S Sadler
U.S. National Science Foundation · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research Training: Self and Family ManagementT32NR008346 · NINR · YALE UNIVERSITY · PI GREY, MARGARET · 2003 to 2018
$4.7M
Toxic Stress and Protective Factors in Multiethnic School Age ChildrenF31NR016385 · NINR · YALE UNIVERSITY · PI CONDON, EILEEN · 2016 to 2017
$80k
NCATS NIH HHS UL1 TR001863NINR NIH HHS F31 NR016385NINR NIH HHS T32 NR008346
6 · The paper itself

Abstract

backgroundResearchers have demonstrated that maternal adverse childhood experiences (ACEs), such as abuse and neglect, are associated with prenatal risk factors and poor infant development. However, associations with child physiologic and health outcomes, including biomarkers of chronic or "toxic" stress, have not yet been explored.

objectivesThe purpose of this study was to examine the associations among past maternal experiences, current maternal posttraumatic stress disorder (PTSD) symptoms, and children's indicators of exposure to chronic stress in a multiethnic sample of mothers and children at early school age (4 to 9 years).

methodsThis cross-sectional study included maternal-child dyads (N = 54) recruited from urban community health centers in New Haven, Connecticut. Mothers reported history of ACEs, family strengths, and current PTSD symptoms. Child measures included biomarkers and health and developmental outcomes associated with chronic stress. Correlational and regression analyses were conducted.

resultsChildhood trauma in mothers was associated with higher systolic blood pressure percentile (ρ = .29, p = .03) and behavioral problems (ρ = .47, p = .001) in children, while maternal history of family strengths was associated with lower salivary interleukin (IL)-1β (ρ = -.27, p = .055), salivary IL-6 (ρ = -.27, p = .054), and body mass index z-scores (ρ = -.29, p = .03) in children. Maternal PTSD symptoms were associated with more child behavioral problems (ρ = .57, p < .001) and higher odds of asthma history (ρ = .30, p = .03). DISCUSSION: Results indicate that past maternal experiences may have important influences on a child's health and affect his or her risk for experiencing toxic stress.

Indexed as

Adverse Childhood ExperiencesChild HealthAdultChildChild BehaviorCross-Sectional StudiesFamily ConflictFemaleHumansMaleMother-Child RelationsParentingSampling StudiesStress, Psychological

Identifiers

PMID30789545
PMCPMC6488406
OpenAlexW2917577397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.