Evidence map›Paper›PMID 30788802›Full record

ArticleFolia microbiologica2019

The influence of N and S poles of static magnetic field (SMF) on Candida albicans hyphal formation and antifungal activity of amphotericin B.

Dariusz Sztafrowski, Jakub Suchodolski, Jakub Muraszko, Karel Sigler, Anna Krasowska

Open access · hybridAbstract read
In one paragraph

Article in Folia microbiologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Dariusz SztafrowskiFaculty of Electrical Engineering, Wrocław University of Science and Technology, ul. Wybrzeże Wyspiańskiego 27, 50-370, Wrocław, Poland.
Jakub SuchodolskiDepartment of Biotransformation, Faculty of Biotechnology, University of Wroclaw, ul. F. Joliot-Curie 14a, 50-383, Wrocław, Poland.
Jakub MuraszkoDepartment of Biotransformation, Faculty of Biotechnology, University of Wroclaw, ul. F. Joliot-Curie 14a, 50-383, Wrocław, Poland.
Karel SiglerInstitute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, 142 20, Prague, Czech Republic.
Anna KrasowskaDepartment of Biotransformation, Faculty of Biotechnology, University of Wroclaw, ul. F. Joliot-Curie 14a, 50-383, Wrocław, Poland. anna.krasowska@uwr.edu.pl.ORCID http://orcid.org/0000-0002-1925-193X
University of Wrocław · PLCzech Academy of Sciences · CZWrocław University of Science and Technology · PL

Funding

Narodowe Centrum Nauki 2016/23/B/NZ1/01928Narodowe Centrum Nauki 2017/25/N/NZ1/00050
6 · The paper itself

Abstract

Due to the increasing number of Candida albicans' infections and the resistance of this pathogenic fungus to drugs, new therapeutic strategies are sought. One of such strategies may be the use of static magnetic field (SMF). C. albicans cultures were subjected to static magnetic field of the induction 0.5 T in the presence of fluconazole and amphotericin B. We identified a reduction of C. albicans hyphal length. Also, a statistically significant additional effect on the viability of C. albicans was revealed when SMF was combined with the antimycotic drug amphotericin B. The synergistic effect of this antimycotic and SMF may be due to the fact that amphotericin B binds to ergosterol in plasma membrane and SMF similarly to MF could influence domain orientation in plasma membrane (PM).

Indexed as

Magnetic FieldsAmphotericin BAntifungal AgentsCandida albicansFluconazoleHyphaeMicrobial Sensitivity TestsMicrobial ViabilityAmphotericin BAntifungal AgentsFluconazole

Identifiers

PMID30788802
PMCPMC6861703
OpenAlexW2915849104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.